Background/objectives: The role of spexin (SPX) in energy metabolism, endocrinal homeostasis, and vasculopathy is emerging. However, scarce data are available about its role in childhood obesity and obesity-related vasculopathy. Hence, we aimed to assess the level of SPX in obese and normal-weight children, and to correlate it with aortic distensibility (AD) and aortic stiffness index (ASI).
View Article and Find Full Text PDFMicroRNAs (miRNAs) have been implicated as regulatory molecules that could play a considerable role in the pathogenesis of different diseases including asthma. This work aims at exploring the role of miR-146a and miR- 106b in the pathogenesis of asthma and their association with asthma severity, IgE, and inflammatory cytokines in asthmatic children. Thirty asthmatic children and twenty age-matched healthy children aged 4-17 years old were enrolled.
View Article and Find Full Text PDFBackground: Asthma as a serious public health problem worldwide exerts a serious load on children's health-related quality of life (HRQOL) and their families.
Objective: We assess the HRQOL of the primary caregivers of Egyptian asthmatic children and adolescents and its relation to HRQOL of their children and asthma severity.
Materials And Methods: A cross-sectional study was conducted on 128 pairs of asthmatic children (7-16 years) and their primary caregivers.
Beta-thalassemia major is a common inherited single-gene disorder. Thalassemic patients are at risk of changes in some important trace elements. To detect alteration of iron, copper, zinc, and calcium serum levels in beta-thalassemia major patients, laser-induced breakdown spectroscopy (LIBS) was used.
View Article and Find Full Text PDFJ Genet Eng Biotechnol
June 2018
Vitamins are evaluated for their role in immunity. Recently, vitamin A received a particular attention as a critical micronutrient for regulating immune system. Therefore, the present study aimed to search for new about vitamin A.
View Article and Find Full Text PDFBackground: Mercury exists worldwide in food, water and air throwing its health hazards on all body systems.
Aim: To show the influence of the presence of mercury in pregnant mothers' blood on its level in the umbilical cord blood; and to display the relationship between the different foodstuff on the mercury levels in pregnant mothers' and umbilical cord blood.
Patients And Methods: This cross-sectional study was conducted on randomly chosen 113 pregnant mothers at the time of labour and on their newborns.
Open Access Maced J Med Sci
March 2018
Background: Body weight concern and belief in adolescent females are of great importance. They are the keys to successful dietary interventions including dietary habits' modifications to practice a healthy diet. This critical phase of transition from childhood to adulthood is the most sensitive stage of behavioural rectification.
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