Combined microneedling with tacrolimus vs tacrolimus monotherapy for vitiligo treatment.

Background: Miconeedling has been used to augment the transdermal drug delivery. Combination modalities may accelerate and improve the repigmentation in vitiligo.

Objective: To determine the efficacy and tolerability of combined microneedling with tacrolimus vs tacrolimus 0.

Successful Treatment of Multiple Common Warts With Intralesional Ozone.

Background: Although there are multiple treatments for warts, wart management remains a challenge. Ozone therapy is an emerging treatment for infectious and noninfectious dermatological diseases.

Objective: To assess intralesional ozone gas safety and efficacy in multiple warts management.

Lactic acid 5% mouth wash vs Kenalog in Orabase 0.1% for treatment and prophylaxis of recurrent aphthous ulcer.

Background: The outcomes of most therapeutic modalities for recurrent aphthous ulcer (RAU) are still unsatisfactory.

Aim: To evaluate lactic acid 5% mouth wash vs Kenalog in Orabase for treatment and prophylaxis of RAU.

Patients/methods: Forty cases with early-onset idiopathic RAU were enrolled in this study.

Subcutaneous methotrexate versus oral form for the treatment and prophylaxis of chronic plaque psoriasis.

Psoriasis is a common inflammatory skin disorder with complex pathomechanisms. Methotrexate (MTX) is an antiproliferative and immunomodulating agent that control psoriasis. The aim of this study is to compare the efficacy of MTX and tolerability to MTX by oral route versus subcutaneous (SC) route.

Combination therapy versus monotherapy in the treatment of recalcitrant warts: A clinical and immunological study.

Background: Treatment of recalcitrant warts represents a continuing therapeutic challenge. Combination therapies can help improve treatment response, decrease adverse effects, and reduce recurrence.

Objective: To compare the efficacy, safety and immunological effects of a combined acitretin-intralesional Candida antigen against acitretin alone and Candida antigen alone for intractable warts.

Evaluation of carboxytherapy and platelet-rich plasma in treatment of periorbital hyperpigmentation: A comparative clinical trial.

Background: Management of periorbital hyperpigmentation (POH) is still a therapeutic challenge. Although different therapeutic modalities are available, the outcomes of most of them are unsatisfactory.

Objectives: To investigate and compare the efficacy and safety of two new modalities in the treatment of POH; the platelet rich plasma (PRP) and the carboxytherapy.