Cross talk between Hsp72, HMGB1 and RAGE/ERK1/2 signaling in the pathogenesis of bronchial asthma in obese patients.

Background: The incidence of obesity-related asthma has shown a remarkable increase.

Objectives: We aimed to explore the role of heat shock protein 72 (Hsp72) and receptor for advanced glycation end products (RAGE) axis with its downstream signaling in the pathogenesis of obesity-related asthma.

Methods: We enrolled a total of 55 subjects and divided them into three groups.