Publications by authors named "Regula C Waeckerlin"
Article Synopsis
- A bacterial pathogen causes serious infections, especially hemorrhagic septicemia in cattle and buffaloes, leading to high mortality and significant socio-economic challenges for smallholder farmers in Africa and Asia.
- Researchers have identified a novel vaccine target, PmSLP-3, which has shown strong protective effects in cattle against serogroup B strains.
- PmSLP-3, combined with Montanide ISA 61, effectively produces long-lasting immunity in cattle, demonstrating protection against both serogroup B and E challenges, with sustained antibody levels found for up to three years after vaccination.
Pasteurella multocida can infect a multitude of wild and domesticated animals, with infections in cattle resulting in hemorrhagic septicemia (HS) or contributing to bovine respiratory disease (BRD) complex. Current cattle vaccines against P. multocida consist of inactivated bacteria, which only offer limited and serogroup specific protection.
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