Development of Movement and Postural Patterns in Full-Term Infants Who Are at Low Risk in Belgium, India, Norway, and the United States.

Objective: The objective of this study was to investigate the influences on motor development in infants who are at low risk from Belgium, India, Norway, and the United States using the General Movement Assessment at 10-16 weeks postterm age.

Methods: This was a cross-sectional study of prospectively enrolled full-term infants at low risk (n = 186). Certified General Movement Assessment observers rated the fidgety movements, quality of the movement patterns, age-adequacy of the movement repertoire, postural patterns, movement character, and overall Motor Optimality Score-Revised (MOS-R).

Baby Observational Selective Control AppRaisal (BabyOSCAR): Scores at 3 months predict functional ability, spastic cerebral palsy distribution, and diagnosis at 2 years.

Aim: To assess the predictive capabilities of the Baby Observational Selective Control AppRaisal (BabyOSCAR) tool, administered at 3 months corrected age, in determining spastic cerebral palsy (CP) outcome, functional abilities, and body topography at 2 years of age or later.

Method: Independent joint motions were measured at age 10 to 16 weeks from video recordings of spontaneous movement using BabyOSCAR in a sample of 75 infants. All included infants had known 2-year outcomes (45 with spastic CP and 30 without CP) including Gross Motor Functional Classification System (GMFCS) levels and CP body distribution.

Baby Observational Selective Control AppRaisal (BabyOSCAR): Convergent and discriminant validity and reliability in infants with and without spastic cerebral palsy.

Aim: To describe the development of an observational measure of spontaneous independent joint motion in infants with spastic cerebral palsy (CP), the Baby Observational Selective Control AppRaisal (BabyOSCAR), and to test its convergent validity and reliability.

Method: A retrospective sample of 75 infants (45 with spastic CP and 30 without CP) at 3 months of age were scored with the BabyOSCAR and compared with diagnosis of spastic CP, limbs affected, and Gross Motor Function Classification level at 2 years of age or later for convergent validity using t-tests, Kruskal-Wallis tests, and Spearman's rank correlation coefficients. BabyOSCAR interrater and test-retest reliability was also evaluated using intraclass correlation coefficients.

Stability of the Motor Optimality Score Revised (MOS-R) in medically complex infants.

Background: The Motor Optimality Score-Revised (MOS-R) is a clinical test of infant spontaneous movement at 3-5 months of age and has been associated with neurodevelopmental outcomes in infants with medical complexity. However the stability of the MOS-R tested at different developmental ages is not yet known.

Aim: To determine if the repeated scoring of the MOS-R remained consistent when tested at two developmental ages in young infants.

Assessing Neonatal Intensive Care Unit (NICU) Graduates Across Varied Settings: A Study on the Feasibility of the Baby Moves App.

We assessed the feasibility of obtaining parent-collected General Movement Assessment videos using the Baby Moves app. Among 261 participants from 4 Chicago NICUs, 70% submitted videos. Families living in higher areas of childhood opportunity used the app more than those from areas of lower opportunity.

Evaluation Protocol for Analogue Intelligent Medical Radars: Towards a Systematic Approach Based on Theory and a State of the Art.

We propose the basis for a systematised approach to the performance evaluation of analogue intelligent medical radars. In the first part, we review the literature on the evaluation of medical radars and compare the provided experimental elements with models from radar theory in order to identify the key physical parameters that will be useful to develop a comprehensive protocol. In the second part, we present our experimental equipment, protocol and metrics to carry out such an evaluation.

Development and Validation of a Deep Learning Method to Predict Cerebral Palsy From Spontaneous Movements in Infants at High Risk.

Importance: Early identification of cerebral palsy (CP) is important for early intervention, yet expert-based assessments do not permit widespread use, and conventional machine learning alternatives lack validity.

Objective: To develop and assess the external validity of a novel deep learning-based method to predict CP based on videos of infants' spontaneous movements at 9 to 18 weeks' corrected age.

Design, Setting, And Participants: This prognostic study of a deep learning-based method to predict CP at a corrected age of 12 to 89 months involved 557 infants with a high risk of perinatal brain injury who were enrolled in previous studies conducted at 13 hospitals in Belgium, India, Norway, and the US between September 10, 2001, and October 25, 2018.

Machine Learning of Infant Spontaneous Movements for the Early Prediction of Cerebral Palsy: A Multi-Site Cohort Study.

Background: Early identification of cerebral palsy (CP) during infancy will provide opportunities for early therapies and treatments. The aim of the present study was to present a novel machine-learning model, the Computer-based Infant Movement Assessment (CIMA) model, for clinically feasible early CP prediction based on infant video recordings.

Methods: The CIMA model was designed to assess the proportion (%) of CP risk-related movements using a time-frequency decomposition of the movement trajectories of the infant's body parts.

The Predictive Accuracy of the General Movement Assessment for Cerebral Palsy: A Prospective, Observational Study of High-Risk Infants in a Clinical Follow-Up Setting.

Background: Early prediction of cerebral palsy (CP) using the General Movement Assessment (GMA) during the fidgety movements (FM) period has been recommended as standard of care in high-risk infants. The aim of this study was to determine the accuracy of GMA, alone or in combination with neonatal imaging, in predicting cerebral palsy (CP).

Methods: Infants with increased risk of perinatal brain injury were prospectively enrolled from 2009-2014 in this multi-center, observational study.

Benchmarking the HRP-2 Humanoid Robot During Locomotion.

In this paper we report results on benchmarking a HRP-2 humanoid robot. The humanoid robots of this serie are known to be very robust. They have been successfully used by several research groups for the design of new motion generation algorithms.

Filtration of ultrafine metallic particles in industry.

Thermal metal spraying, metal cutting and arc welding processes generate large quantities of ultrafine particles that cause the irreversible clogging of industrial filters. The aim of the study performed was to identify the causes of the clogging of cartridge filters and investigate other paths for cleaning them. This study required the development of a test bench capable of reproducing a thermal spraying process to test the performances of different filtration techniques.

Ultrafine particles emitted by flame and electric arc guns for thermal spraying of metals.

The ultrafine aerosol emitted by thermal spraying of metals using flame and electric arc processes has been characterized in terms of particle size distribution and emission rates based on both particle number and mass. Thermal spraying of Zn, Zn/Al, and Al was studied. Measurements taken using an electrical low pressure impactor and a condensation nucleus counter reveal an aerosol made up of very fine particles (80-95% of number distribution <100 nm).

Methods for measuring performance of vehicle cab air cleaning systems against aerosols and vapours.

Vehicle cabs equipped with an effective air cleaning and pressurization system, fitted to agricultural and off-road machineries, isolate drivers from the polluted environment, in which they are likely to work. These cabs provide protection against particulate and gaseous pollutants generated by these types of work activities. Two laboratory methods have been applied to determining the performance characteristics of two cabs of different design, namely, optical counting-based measurement of a potassium chloride (KCl) aerosol and fluorescein aerosol-based tracing.

Minor physical anomalies are not increased in the offspring of mothers with systemic lupus erythematosus.

Objective: To determine the incidence and type of minor physical anomalies (MPAs) in infants born to mothers with systemic lupus erythematosus (SLE).

Methods: Each trimester, pregnant women with SLE were assessed for disease activity, prescribed drug use, and exposure to tobacco, alcohol, and illicit drugs through a self reported questionnaire. Infant examinations were performed on 30/39 (77%) live births in women with SLE and the incidence of MPAs determined.

Measuring the emission rate of an aerosol source placed in a ventilated room using a tracer gas: influence of particle wall deposition.

A method to measure the emission rate of an airborne pollutant source using a tracer gas was tested in the case of an aerosol source. The influence of particle deposition on the walls of a test room of 72 m3 was studied. The deposition rate of an aerosol of MgCl2 was determined by means of two methods: one based on measuring the aerosol concentration decay inside the ventilated room, the other based on calculation of the material mass balance.

Measurement of the emission rate of an aerosol source--comparison of aerosol and gas transport coefficients.

A measuring method of the emission rate of an atmospheric pollutant source, based on the use of a tracer gas (helium) and developed in the case of a gaseous source, was tested for an aerosol source. The influence of both particle sedimentation and wall depositions was studied. The transport coefficients of the tracer gas and of alumina particles of various particle sizes (MMAD from 8 to 36 microns) were measured on a vertical axis close to the source, in a 71 m3 room swept by a piston flow.

Separation efficiency of a wood dust collector-field measurement using a fluorescent aerosol.

Given the dangerous nature of the dust emitted in the wood industry, the quality of the recycled air in the work premises after cleaning must be strictly controlled.A method of measuring the efficiency of a wood dust collector as a function of the particle diameter has been developed using a fluorescein tracer aerosol generated upstream of the equipment. The separation efficiency is determined from the particle size mass distribution of the tracer, both upstream and downstream, measured by means of two cascade impactors.

[Whole body irradiation].

Total body irradiation produces a sufficient immunosuppression to prevent an allograft rejection. It can be used with chemotherapy as an "intensive" treatment aiming at the complete eradication of a malignancy--with the resulting bone marrow aplasia needing an autologous or allogeneic transplantation. In either case, a dose of some 10 Gy has to be delivered in the whole body, in one session at low dose rate or fractionated between several sessions.

[Medulloblastoma: analysis of 14 cases treated at the J. Bordet Institute and literature review].

Between 1966 and 1986, 14 patients with histologically verified cerebellar medulloblastomas were seen at J. Bordet Institute after total (4 cases) or partial (10 cases) tumor removal. Twelve received postoperative irradiation after some courses of chemotherapy (Vincristine, Procarbazine, Methotrexate) for 5.

Breast conserving treatment for early cancers. Rationales, perspectives and techniques.

The paper reviews the rationale for breast conserving treatment for early cancers; the different studies are presented as well as the technical limitations and problems involved by surgery and radiotherapy. Nowadays, breast conserving treatment includes a limited resection of the tumor followed by a course of radiation. This treatment allows to preserve the breast and spares a mutilation to the woman.