Publications by authors named "Regis Mariano Andrade"
Article Synopsis
- Chronic hepatitis C (CHC) is linked to liver damage due to the immune response to HCV antigens, with high levels of IL-1β, IL-6, and IL-17 found in patients.
- A notable increase in core-specific IL-6 and IL-17 T cells occurs in patients with more severe liver lesions, as shown by the Metavir scale.
- CHC patients have an elevated percentage of Treg cells, particularly those with advanced fibrosis, but a low proportion of CD39 Treg subsets, indicating an imbalance in T cell populations associated with liver fibrosis severity.
Glucuronoxylomannan (GXM), the major capsular polysaccharide of Cryptococcus neoformans, is the most important virulence factor of this fungus. We analyzed the molecular events related to protective immune responses against a non-encapsulated strain of C. neoformans, mediated by murine splenic CD4(+) T lymphocytes in vitro, and the impact of GXM addition upon these events.
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