Aqueous humor sCD44 concentration and visual field loss in primary open-angle glaucoma.

Purpose: To correlate aqueous humor soluble CD44 (sCD44) concentration, visual field loss, and glaucoma risk factors in primary open-angle glaucoma (POAG) patients.

Methods: Aqueous samples were obtained by paracentesis from normal and glaucoma patients who were undergoing elective surgery and analyzed for sCD44 concentration by enzyme-linked immunosorbent assay.

Results: In normal aqueous (n=124) the sCD44 concentration was 5.

Detection of the free acid of bimatoprost in aqueous humor samples from human eyes treated with bimatoprost before cataract surgery.

Purpose: To determine whether bimatoprost is hydrolyzed to its free acid after topical application in humans in vivo.

Design: Prospective, masked, and vehicle controlled.

Participants: Thirty-one eyes of 31 patients with cataracts.