Publications by authors named "Regina Ritter"
Background: Large parts of Malawi`s population lack access to health care. A high burden of disease, chronic poverty, and a growing population accelerate the need for extending and improving health care. One region that is struggling with service provision is Malawi´s rural district Phalombe.
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- SiiE is a large adhesive protein from Salmonella enterica that aids in the bacteria's attachment to host cells through a specific secretion system, emphasizing its role in infection.* -
- The structure of SiiE's bacterial Ig-like domains has been mapped, revealing that these domains contain unique binding sites for calcium ions, essential for its function.* -
- Molecular simulations show that calcium binding gives SiiE a rigid rod-like shape, allowing it to extend past the bacterial layer and facilitate stronger adhesion to host cells.*