Publications by authors named "Regiane M A Sampaio"
Hepatitis C and Human Pegivirus Coinfection in Patients with Chronic Hepatitis C from the Brazilian Amazon Region: Prevalence, Genotypes and Clinical Data.
Patrícia Ferreira Nunes Evelen da Cruz Coelho Joseane Rodrigues da Silva Camila Carla da Silva Costa Regiane Miranda Arnund Sampaio
Viruses
September 2023
Article Synopsis
- - The study investigates the prevalence of human pegivirus-1 (HPgV-1) in patients with hepatitis C virus (HCV) in Belém, Brazil, finding that about 28% of HCV-infected individuals are also infected with HPgV-1.
- - Out of 147 participants, 72.1% were solely infected with HCV, while 27.9% were coinfected; HPgV-1 genotypes 1 and 2 were most common among those with HPgV-1.
- - The researchers did not find significant differences in risk factors or the clinical impact of HPgV-1 on HCV, indicating high prevalence but unclear effects on HCV progression,
Hepatitis B and C are the most common causes of liver disease worldwide. The two infections share many similarities such as a global distribution, the same routes of transmission, hepatotropism, and the ability to cause chronic infection. The consequences of HBV/HCV coinfection are still being studied.
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