The natural history of ALS: Baseline characteristics from a multicenter clinical cohort.

Background: Amyotrophic lateral sclerosis (ALS) is a rare disease with urgent need for improved treatment. Despite the acceleration of research in recent years, there is a need to understand the full natural history of the disease. As only 40% of people living with ALS are eligible for typical clinical trials, clinical trial datasets may not generalize to the full ALS population.

Impact of pharmacist intervention on completion of recombinant zoster vaccine series in a community pharmacy.

Objectives: The objectives of this study were to analyze the impact a pharmacist phone call has played on patients completing the 2-dose shingles vaccine series and to explore the effect that patient cost has on the second dose administration.

Methods: A retrospective cohort study design was used to evaluate whether patients who had a pharmacist phone call intervention were more likely to return for their second recombinant zoster vaccine (RZV) dose than patients who did not have a pharmacist phone call intervention. In addition, the impact of immunization cost on series completion was analyzed.