Nitrous oxide for pain management during in-office hysteroscopic sterilization: a randomized controlled trial.

Objectives: To evaluate whether inhaled nitrous oxide with oxygen (NO/O) is associated with less pain compared to oral sedation for pain management during in-office hysteroscopic sterilization.

Study Design: This double blinded randomized controlled trial enrolled women undergoing in-office hysteroscopic sterilization. All participants received pre-procedure intramuscular ketorolac and a standardized paracervical block.