Publications by authors named "Reena Masih"
Article Synopsis
- Study examines neurocognitive impairment in HIV+ individuals despite effective antiretroviral therapy (ART), highlighting improved cognitive function after ART initiation in resource-limited countries.* -
- The research involved a randomized clinical trial assessing cognitive performance and compared it to data from HIV-negative participants, establishing categories of neurocognitive impairment in HIV+ individuals.* -
- Findings revealed that nearly half of the participants had some level of neurocognitive impairment at the start, but significant improvements were noted over time with ART, particularly among those with more severe impairments.*
Article Synopsis
- The study compared neurological and neuropsychological performance in HIV-1-infected individuals in resource-limited settings receiving three ART regimens from the World Health Organization, with a focus on the impact of tuberculosis (TB) on these outcomes.
- Over 860 participants were analyzed, revealing that those with TB coinfection scored lower on fine motor skills tests and reported a significantly lower quality of life and productivity.
- The findings indicate that TB coinfection negatively affects neuropsychological function and overall well-being in HIV-1-infected individuals.
Objectives: People living with HIV have increased Human Papillomavirus (HPV) related lesions and malignancies. We describe HPV DNA recovered from the cervix and anal canal, explore the effect of vaccination on HPV detection, and examine the durability of vaccine titers in women living with HIV-1 who were vaccinated with the quadrivalent HPV vaccine.
Methods: AIDS Clinical Trials Group A5240 was a prospective study of the quadrivalent HPV (qHPV) vaccine in 315 HIV-1 infected women in three CD4 strata (A: >350, B; 201-350, C: ≤200 cells/mm).
Little is known about how the prevalence and incidence of neurological disease in HIV-infected patients in resource-limited settings. We present an analysis of neurological and neurocognitive function in antiretroviral naïve individuals in multinational resource-limited settings. This prospective multinational cohort study, a substudy of a large international randomized antiretroviral treatment trial, was conducted in seven low- and middle-income countries in sub-Saharan Africa, South America, and Asia.
View Article and Find Full Text PDFTargeting canarypox (CP)-HIV vaccine to dendritic cells (DCs) elicits anti-HIV-1 immune responses in vitro. We conducted a phase I/II clinical trial to evaluate whether adding DC to a CP-HIV vaccine improved virologic control during analytic treatment interruption (ATI) in HIV-1-infected subjects. Twenty-nine subjects on suppressive antiretroviral therapy were randomized to vaccination with autologous DCs infected with CP-HIV+keyhole limpet hemocyanin (KLH) (arm A, n=14) or CP-HIV+KLH alone (arm B, n=15).
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