Recent Adv Antiinfect Drug Discov
February 2025
This review discusses the use of hydrogel systems for intravaginal drug delivery, specifically antibacterial, anti-trichomonas, and anti-fungal regimens for managing and treating gynecological infections, particularly vaginal candidiasis. About 80% of females worldwide have encountered candida albicans, the root cause of vaginal candidiasis [VC]. This infection is manifested by inflammation, itching, erythema, dyspareunia, and pain in the infected vaginal mucosal area.
View Article and Find Full Text PDFPlant Cell Rep
October 2021
Charcoal rot (CR) is a major disease of soybean, which is caused by Macrophomina phaseolina (Mp). Increasing temperatures and low rainfall in recent years have immensely benefitted the pathogen. Hence, the search for genetically acquired resistance to this pathogen is essential.
View Article and Find Full Text PDFThe mildew locus O (Mlo) gene family is ubiquitous in land plants. Some members of this gene family are involved in negative regulation of powdery mildew resistance, while others are involved in several other biological functions. Mlo proteins have characteristic seven transmembrane domains and a calmodulin-binding domain at their C-termini, and are associated with plasma membrane.
View Article and Find Full Text PDFThe Mlo gene was discovered in barley because the mutant 'mlo' allele conferred broad-spectrum, non-race-specific resistance to powdery mildew caused by Blumeria graminis f. sp. hordei.
View Article and Find Full Text PDFPowdery mildew locus O (Mlo) gene family is one of the largest seven transmembrane protein-encoding gene families. The Mlo proteins act as negative regulators of powdery mildew resistance and a loss-of-function mutation in Mlo is known to confer broad-spectrum resistance to powdery mildew. In addition, the Mlo gene family members are known to participate in various developmental and biotic and abiotic stress response-related pathways.
View Article and Find Full Text PDFThe custard apple (Annona squamosa) fruits were procured from local market, irradiated with radiation doses 0, 0.25, 0.50, 0.
View Article and Find Full Text PDFPhysiol Mol Biol Plants
January 2012
Drought tolerance is the essential trait that needs to be incorporated in cereal crops, particularly those grown under the rainfed cultivation. Drought tolerance being contributed by several regions of the genome requires identification of these regions, using suitable molecular markers. Therefore, present investigation was aimed at analyzing the genetic diversity present among the cultivars of rainfed and the irrigated areas with respect to the drought tolerant trait.
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