Introduction: Type 1 diabetes mellitus (T1DM) is an autoimmune disease with the development of abnormal immune responses to specific β-cell autoantigens in addition to other organ-specific autoimmunity. The most frequent associated disorders are thyroid dysfunctions and celiac disease. There are limited studies in the current literature on the prevalence of associated autoimmunity, especially multiple, in children and adolescents with T1DM and Type 2 diabetes mellitus (T2DM).
View Article and Find Full Text PDFIntroduction: Familial type 1 diabetes mellitus (FT1DM) comprises parent-offspring and sib-pair subgroups. The clinical and genetic characteristics of FT1DM cases with and without affected family members have been previously studied with varying results. Some investigators found similarity of presenting features whereas others reported significant differences between the two groups.
View Article and Find Full Text PDFIntroduction: Diagnoses of type 1 DM (T1DM) and type 2 diabetes mellitus (T2DM) in youths present a substantial clinical and public health burden. The aim of this study was to determine the incidence and trend of T1DM and T2DM, among children aged 0-14 years, in Qatar.
Methods: This prospective cohort study was performed to ascertain all new cases of T1DM and T2DM 2 in Qatar as per the registry of the National Paediatric Diabetes Centre (the only tertiary care center treating children with DM in Qatar.