Publications by authors named "Reem I ElKorashy"
Objective: To investigate the effect of selective manual therapy (MT) techniques on chest expansion, pulmonary function (forced vital capacity [FVC], forced expiratory volume in 1 s [FEV1], and FEV1/FVC ratio), craniovertebral angle (CVA), kyphosis angle, functional capacity, and dyspnea in patients with chronic obstructive pulmonary disease (COPD).
Methods: A parallel double-blinded randomized controlled trial involved 52 male subjects with a mean age of 56.23 ± 3.
A Systematic Review of Novel Therapies of Pulmonary Arterial Hypertension.
Am J Cardiovasc Drugs
January 2024
Article Synopsis
- - Pulmonary arterial hypertension (PAH) is a serious, progressive condition that causes increased pressure in the lungs, leading to heart failure, and researchers are exploring new treatments to alleviate symptoms and improve patient outcomes.
- - This systematic review analyzed 8 randomized controlled trials focusing on the effectiveness of various potential treatments, including Rho-kinase inhibitors, BMP2 inhibitors, estrogen inhibitors, and AMPK activators, but faced challenges in conducting a meta-analysis due to differences in study designs and outcome measures.
- - Key findings suggest that metformin and the BMP2 inhibitor sotatercept show promise for modifying PAH, while the effects of other drugs, such as fasudil and anastrozole, require further long-term study to
Background: Pulmonary hypertension "PH" is considered a serious cardiovascular disease. World Health Organization divided PH into groups depending on many factors like pathological, hemodynamic, and clinical pictures. Lately, various micro-RNAs "miRNAs" and other novel biomarkers like endoglin and asymmetric dimethylarginine "ADMA" might have a role in diagnosis of PH and may differentiate between pulmonary arterial hypertension "PAH" and non-PAH.
View Article and Find Full Text PDFBackground: Weaning failure is common in mechanically ventilated patients, and if ultrasound can predict weaning outcome remains controversial. The purpose of this study was to evaluate the diaphragmatic function (thickness and excursion) measured by ultrasound as a predictor of the extubation outcome.
Methods: We included 62 mechanically ventilated patients from the chest intensive care unit in this study.