Publications by authors named "Reem AlQusaimi"
Scabies is a common skin infestation with a high prevalence in populations with low socioeconomic conditions. The topical application of benzyl benzoate (BB) is effective due to its neurotoxic effects on mites; however, its efficacy remains inconsistent and ambiguous across studies. In contrast, topical permethrin 5% has emerged as one of the most widely prescribed treatments for scabies, attributed to its relatively high efficacy.
View Article and Find Full Text PDFHenoch-Schönlein purpura (HSP), or anaphylactoid purpura, is an acute, self-limited small-vessel vasculitis commonly affecting children aged 3-10. It features a classic tetrad: palpable non-thrombocytopenic purpura, abdominal pain, polyarthralgia, and renal involvement. While the prognosis is generally favorable, long-term outcomes depend on renal involvement.
View Article and Find Full Text PDFArticle Synopsis
- Oral lichen planus (OLP) is a potentially serious condition of the mouth, and this study explores the potential of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) as alternatives to corticosteroids for treatment.
- A systematic review of existing randomized controlled trials was conducted, analyzing data from 8 studies involving 157 patients to compare PRP and PRF against corticosteroids based on changes in lesion size, pain, and clinical scores.
- The findings indicate no significant differences between PRF, PRP, and corticosteroids in most outcomes, but PRF consistently ranked highest in reducing lesion sizes and pain scores at various weeks, suggesting it could be a more effective treatment alternative in managing OLP.
Article Synopsis
- The study investigates a specific genetic variant in the endoplasmic reticulum membrane protein complex, linked to a rare condition called cerebellar atrophy, visual impairment, and psychomotor retardation (CAVIPMR), in individuals from five Kuwaiti families.
- Researchers conducted exome sequencing and confirmed the presence of a pathogenic variant [c.245C>T:p.(Thr82Met)] in these families, previously associated with similar symptoms in a Turkish family.
- Clinical features observed in the affected individuals included developmental delays, hypotonia, visual problems, and brain imaging revealed cerebellar atrophy, highlighting the severe impact of the variant on neurological development.
Article Synopsis
- - Pemphigus herpetiformis (PH) is a rare autoimmune skin condition that mostly affects adults, but it's extremely uncommon in young children, like the three-year-old girl in the case study.
- - The child exhibited skin issues resembling other conditions, and a biopsy revealed several specific features, including inflammation and blisters.
- - Treatment with clobetasol ointment and dapsone led to significant improvement in her symptoms, highlighting the need to recognize PH in pediatric cases and encouraging more research to understand it better.