Publications by authors named "Reece P Summers"
Nucleic Acids Res
January 2022
Article Synopsis
- Upf1, typically studied for its role in mRNA decay, shows a significant association with active genes in the fission yeast Schizosaccharomyces pombe, as indicated by high-throughput ChIP data.
- This association is sensitive to RNase, correlates with RNA polymerase II (Pol II) transcription, and affects mRNA expression levels.
- In Upf1-deficient cells, there are notable changes in Pol II occupancy and an increased sensitivity to transcription elongation inhibitors, suggesting Upf1 may play a critical role in regulating gene transcription and Pol II phosphorylation.
