Confined Polyethylene Glycol Anchored in Kaolinite as High Ionic Conductivity Solid-State Electrolyte for Lithium Batteries.

Solid-state electrolytes (SSEs) have garnered significant attention as critical materials for enabling safer, energy-dense, and reversible electrochemical energy storage in batteries. Among the various types of solid electrolytes developed, composite polymer electrolytes (CPEs) have stood out as some of the most promising candidates due to their well-rounded performance. In this study, we choose polyethylene glycol (PEG) as the covalent grafting intercalant and lithium perchlorate as carrier source to prepare a fast lithium ion conductor, K-PEG-Li doped with clay-based active filler as a CPE.

The use of echocardiography compared to electrocardiogram when screening for left ventricular hypertrophy in hypertensive patients: A cross-sectional study.

Left ventricular hypertrophy (LVH) is often used as an indicator to assess hypertension-mediated organ damage (HMOD), alongside hypertensive retinopathy (HR) and nephropathy. Assessment of HMOD is crucial when making decisions about treatment optimization. Despite longstanding debate over its reliability to detect LVH, it is common practice to perform an electrocardiogram (ECG) instead of directly assessing left ventricular mass with echocardiography.

Molecular Networking-Based Metabolome, In Vitro Antidiabetic and Anti-Inflammatory Effects of (Vahl) Hepper & J.R.I. Wood.

(Vahl) Hepper & J.R.I.

Ultra-Early and Short-Term Tranexamic Acid Treatment in Patients With Good- and Poor-Grade Aneurysmal Subarachnoid Hemorrhage.

Background And Objectives: The results of the ULTRA trial showed that ultra-early and short-term treatment with tranexamic acid (TXA) does not improve clinical outcome after aneurysmal subarachnoid hemorrhage (aSAH). Possibly, the lack of a beneficial effect in all patients with aSAH is masked by antagonistic effects of TXA in certain subgroups. In this post hoc subgroup analysis, we investigated the effect of TXA on clinical outcome in patients with good-grade and poor-grade aSAH.

Effects of seasonal variation on phytochemicals contributing to the antimalarial and antitrypanosomal activities of using a metabolomic approach.

This study involves the investigation of various plant parts of (Vahl) Hepper and J.R.I.

Tranexamic Acid After Aneurysmal Subarachnoid Hemorrhage: Post Hoc Analysis of the ULTRA Trial.

Background And Objectives: The ULTRA trial showed that ultra-early and short-term tranexamic acid treatment after subarachnoid hemorrhage did not improve clinical outcome at 6 months. An expected proportion of the included patients experienced nonaneurysmal subarachnoid hemorrhage. In this post hoc study, we will investigate whether ultra-early and short-term tranexamic acid treatment in patients with aneurysmal subarachnoid hemorrhage improves clinical outcome at 6 months.

Nanomaterials for the electrochemical nitrogen reduction reaction under ambient conditions.

As an important chemical product and carbon-free energy carrier, ammonia has a wide range of daily applications in several related fields. Although the industrial synthesis method using the Haber-Bosch process could meet production demands, its huge energy consumption and gas emission limit its long-time development. Therefore, the clean and sustainable electrocatalytic N reduction reaction (NRR) operating under conditions have attracted great attention in recent years.

bridging nanotwinned all-solid-state Z-scheme g-CN/CdCO/CdS heterojunction photocatalyst by metal oxide for H evolution.

Nanotwin and all-solid-state (ASS) Z-scheme heterojunction engineering are two widely used strategies for improving photocatalytic activity in H production. However, both strategies fail to produce a satisfactory effect when used alone due to their own limitations. Hence, combining nanotwin and ASS Z-scheme heterojunction engineering is expected to improve photocatalytic activity effectively.

Pre- and Interhospital Workflow Times for Patients With Large Vessel Occlusion Stroke Transferred for Endovasvular Thrombectomy.

Patients with large vessel occlusion (LVO) stroke are often initially admitted to a primary stroke center (PSC) and subsequently transferred to a comprehensive stroke center (CSC) for endovascular thrombectomy (EVT). This interhospital transfer delays initiation of EVT. To identify potential workflow improvements, we analyzed pre- and interhospital time metrics for patients with LVO stroke who were transferred from a PSC for EVT.

Agar Acts as Cathode Microskin to Extend the Cycling Life of Zn//α-MnO Batteries.

The Zn/MnO battery is a promising energy storage system, owing to its high energy density and low cost, but due to the dissolution of the cathode material, its cycle life is limited, which hinders its further development. Therefore, we introduced agar as a microskin for a MnO electrode to improve its cycle life and optimize other electrochemical properties. The results showed that the agar-coating layer improved the wettability of the electrode material, thereby promoting the diffusion rate of Zn and reducing the interface impedance of the MnO electrode material.

An Artificial Polyacrylonitrile Coating Layer Confining Zinc Dendrite Growth for Highly Reversible Aqueous Zinc-Based Batteries.

Aqueous rechargeable zinc-metal-based batteries are an attractive alternative to lithium-ion batteries for grid-scale energy-storage systems because of their high specific capacity, low cost, eco-friendliness, and nonflammability. However, uncontrollable zinc dendrite growth limits the cycle life by piercing the separator, resulting in low zinc utilization in both alkaline and mild/neutral electrolytes. Herein, a polyacrylonitrile coating layer on a zinc anode produced by a simple drop coating approach to address the dendrite issue is reported.

Second intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis (SID-GBS): a double-blind, randomised, placebo-controlled trial.

Background: Treatment with one standard dose (2 g/kg) of intravenous immunoglobulin is insufficient in a proportion of patients with severe Guillain-Barré syndrome. Worldwide, around 25% of patients severely affected with the syndrome are given a second intravenous immunoglobulin dose (SID), although it has not been proven effective. We aimed to investigate whether a SID is effective in patients with Guillain-Barré syndrome with a predicted poor outcome.

Ultra-early tranexamic acid after subarachnoid haemorrhage (ULTRA): a randomised controlled trial.

Background: In patients with aneurysmal subarachnoid haemorrhage, short-term antifibrinolytic therapy with tranexamic acid has been shown to reduce the risk of rebleeding. However, whether this treatment improves clinical outcome is unclear. We investigated whether ultra-early, short-term treatment with tranexamic acid improves clinical outcome at 6 months.

In Vitro Studies on Antioxidant and Anti-Parasitic Activities of Compounds Isolated from Sond.

As part of an ongoing study of natural products from local medicinal plants, the methanol extract of stem bark of Sond was investigated for biological activity. Column chromatography and preparative thin-layer chromatography were used to isolate lupeol (), raucaffricine (), -methylsarpagine (), and spegatrine (). The crude extract, fractions and isolated compounds were tested for anti-oxidant, antitrypanosomal and anti-proliferation activities.

Presentation outside office hours does not negatively influence treatment times for reperfusion therapy for acute ischemic stroke.

Background: Treatment outside office hours has been associated with increased workflow times for intravenous thrombolysis (IVT) in acute ischemic stroke (AIS). Limited data suggest that this "off-hours effect" also exists for endovascular treatment (EVT). We investigated this phenomenon in a well-organized acute stroke care region in the Netherlands.

Isolation, Chemical Profile and Antimalarial Activities of Bioactive Compounds from Sond.

In this study, the chemical profile of a crude methanol extract of Sond was determined by ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). Column chromatography and preparative thin layer chromatography were used to isolate three indole alkaloids (raucaffricine, -methylsarpagine and spegatrine) and one triterpenoid (lupeol). The antiplasmodial activity was determined using the parasite lactate dehydrogenase (pLDH) assay.

Association between i.v. thrombolysis volume and door-to-needle times in acute ischemic stroke.

Centralization of intravenous thrombolysis (IVT) for acute ischemic stroke in high-volume centers is believed to improve the door-to-needle times (DNT), but limited data support this assumption. We examined the association between DNT and IVT volume in a large Dutch province. We identified consecutive patients treated with IVT between January 2009 and 2013.

Bioactive compounds from the endophytic fungus Fusarium proliferatum.

The crude extract of an endophytic fungus isolated from Syzygium cordatum and identified as Fusarium proliferatum showed 100% cytotoxicity against the brine shrimp Artemia salina at 100 μg/mL. Seven coloured, biologically active metabolites - including ergosta-5,7,22-trien-3β-ol, nectriafurone-8-methyl ether, 9-O-methyl fusarubin, bostrycoidin, bostrycoidin-9-methyl ether and 8-hydroxy-5,6-dimethoxy-2-methyl-3-(2-oxo-propyl)-1,4-naphthoquinone- were isolated from the extract.

The genus Pluchea: phytochemistry, traditional uses, and biological activities.

In this review, literature data on phytochemical and biological investigations on the genus Pluchea are compiled. Pluchea is a genus of flowering plants in the Asteraceae family and comprises ca. 80 species distributed mainly in Northern and Southern America, Africa, Asia, and Australia.

Isolation and relative stereochemistry of lippialactone, a new antimalarial compound from Lippia javanica.

The aerial parts of Lippia javanica were investigated for biologically active chemical compounds present in them. Chromatographic separation of the ethyl acetate extract of the aerial parts yielded a new antimalarial α-pyrone, lippialactone (2). Lippialactone is active against the chloroquine-sensitive D10 strain of Plasmodium falciparum with an IC50 value of 9.

Chemistry and biology of genus Vismia.

Context: Many herbal remedies have been employed in the treatment and management of various human ailments since the beginning of human civilization. Vismia is an extensive genus of the family Hypericaceae and consists of small trees inhabiting the tropical and subtropical regions of South and Central America. Within the framework of an International Cooperative Biodiversity Groups project, three Vismia species were studied for their potential anticancer activity.