Publications by authors named "Redwane Rakza"

Background: Following implantation/replacement of an implantable cardioverter-defibrillator, patients are legally subjected to variable lengths of driving restrictions based on the indication (1 and 3 months after primary and secondary prevention, respectively; 1 week after device replacement).

Aim: To assess the incidence of ventricular arrhythmia during the theoretical driving restriction period in a large cohort of patients.

Methods: Patients who underwent implantable cardioverter-defibrillator implantation for primary or secondary prevention or device replacement between 2015 and 2021 were included retrospectively.

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Article Synopsis
  • The study introduces a new technique called multielectrode catheter-induced ectopy mapping (MECIE mapping) to help locate the origins of infrequent premature ventricular complexes (PVCs) for effective ablation treatment.
  • Researchers enrolled 29 patients with infrequent PVCs and used MECIE mapping to create a detailed local activation time map, achieving high concordance with the clinical PVCs.
  • After an average follow-up of about 13 months, 93.1% of the patients experienced an 80% or greater reduction in PVCs, indicating that MECIE mapping is a promising strategy for successful PVC ablation.
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Quinidine, the first antiarrhythmic drug, was widely used during the 20th century. Multiple studies have been conducted to provide insights into the pharmacokinetics and pleiotropic effects of Class Ia antiarrhythmic drugs. However, safety concerns and the emergence of new drugs led to a decline in their use during the 1990s.

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