Publications by authors named "Redouane Niamane"

Hodgkin's lymphoma (HL), also known as Hodgkin lymphoma or Hodgkin disease, is a type of malignancy that originates in B lymphocytes, which are a type of white blood cells involved in the immune system. It is characterized by the presence of abnormal Reed-Sternberg cells within the lymph nodes or other lymphoid tissues. Bone involvement of HL is exceptional, which can be localized or part of a disseminated disease.

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In 2017, the Moroccan Society of Rheumatology (SMR) issued guidelines for the treatment of severe ankylosing spondylitis. The emergence of new therapeutic classes, the update of international guidelines for axial SpA and psoriatic arthritis, and the diagnostic and therapeutic challenges encountered by rheumatologists has led to the development of recent SMR guidelines for the management of SpA patients. A group-work included rheumatologists, specialists in physical medicine and rehabilitation, and epidemiologists from various sectors was tasked with writing these recommendations based on a literature review, then adapting them to the national context.

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The advent of new therapeutic classes and the updating of international recommendations have justified the development of recent recommendations by the Moroccan Society of Rheumatology. Methods Guidelines were drafted by a core steering committee after performing a literature search. A multidisciplinary task force, including three fellows, eleven rheumatologists, a specialist in physical medicine and rehabilitation, an epidemiologist from hospital-university, hospital and liberal sectors and one patient assessed the Best Practice Guidelines using 2 rounds of anonymous online voting by modified Delphi process.

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Article Synopsis
  • The study investigated characteristics of late-onset spondyloarthritis (SpA) in patients over 45 years old, comparing them to those with early-onset SpA aged 45 or younger.
  • Data were collected from the Moroccan registry of biological therapies, involving 194 patients, with 31 classified as having late-onset SpA.
  • Key findings included that late-onset SpA patients had significantly more tender and swollen joints, higher rates of depression and fibromyalgia, but lower occurrences of coxitis compared to early-onset patients.
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Objectives: To describe and analyse the prevalence of extra-articular manifestations (EAMs) including acute anterior uveitis (AAU), psoriasis and inflammatory bowel disease (IBD) in patients with ankylosing spondylitis (AS) in the Moroccan registry of biological therapies in rheumatic diseases RBSMR (Registre des Biothérapies de la Société Marocaine de Rhumatologie).

Methods: A cross-sectional, multicentre and analytical study based on the RBSMR database, which included 170 AS. Incidence rates for the development of AAU, psoriasis and IBD were calculated, and risk factors were analysed.

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  • Before starting biotherapy for rheumatic diseases, patients should be screened for latent tuberculosis infection (LTBI), and a study was conducted to assess the prevalence of LTBI in Moroccan patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA).
  • The study included 259 patients (94 with RA and 165 with SpA) and found an overall LTBI prevalence of 21.6%, with higher rates in SpA (24.8%) compared to RA (15.9%).
  • Demographic and clinical characteristics showed no significant differences between LTBI-positive and negative patients, indicating that being in a TB-endemic country like Morocco presents a notable risk for both RA and SpA patients.
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Introduction: the aim of our study is to determine, from data of the Moroccan register of biotherapies, the factors influencing the choice of the first prescribed biological treatment.

Methods: cross-sectional multicenter study including rheumatoid arthritis patients who were initiated the first biological treatment either: Rituximab, an anti-TNF, or Tocilizumab. The determinants related to the patient and disease have been gathered.

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The aim of the present study was to determine the prevalence of human leukocyte antigen HLA-B27 in Moroccan healthy controls and in patients with ankylosing spondylitis (AS), and to analyze the correlation between HLA-B27 and AS in Moroccan patients. The prevalence of HLA-B27 was determined by evaluating the number of HLA-B27-positive samples in 128 healthy subjects and in 53 patients diagnosed with AS according to the ESSG and AMOR criteria. HLA-B27 was determined by the polymerase chain reaction using sequence-specific primers.

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  • - A nationwide telephonic survey in Morocco aimed to assess the prevalence of chronic pain with neuropathic characteristics (NC) among the general population using a random sample of households from 16 regions.
  • - Out of 5,328 respondents, 21% reported chronic daily pain lasting over three months, with a point prevalence of chronic pain with NC at 10.6%, significantly higher among women, older adults, and those from lower socioeconomic backgrounds.
  • - Findings suggest that chronic pain with NC may be more common and severe than previously recognized, particularly affecting the lower limbs and exhibiting higher intensity and duration compared to non-neuropathic chronic pain.
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Background: Verbal descriptors of pain can provide a basis for distinguishing neuropathic pain (NP) from pain of non-neuropathic origin. Much research has been undertaken to develop screening tools for this purpose. The DN4 questionnaire (NP in four questions), is one of theses tools, which was developed and validated in French in 2005.

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Background: Deep pelvic abscess is a well-known infective complication in gynecologic practice. However, sacral osteomyelitis has been reported rarely. We describe sacral infection presenting three years after abdominal hysterectomy and point out the difficulty in management.

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