[The paradoxical effect of the lymphocytes during the filtration of thrombocyte-rich heparinized plasma].

Filtration of platelet-rich heparinized plasma deprived lymphocytes and contained lymphocytes was investigated in 21 donors. Filtration of both plasmas was performed through 5 microns-pore nuclear filters at the constant perfusion pressure 100 cm H2O. The plasma contained lymphocytes filtered by 80% better, than the lymphocyte-deprived plasma.

[Role of leukocyte adhesion in filterability of blood cell suspensions].

We investigated blood cells suspension filterability of 16 donors. The filtration was performed trough 5 microns-pore nuclear filters at constant perfusion pressure 10(5) din/cm2. We estimated also the adherence of leukocytes and platelets on nylon.

[Leukocyte filterability in whole blood].

There was investigated the leukocyte and erythrocyte filtration in blood of 25 donors men. The blood filtration was performed through 5 m pores of nuclear filters at constant perfusion pressure 100 cm H2O. Erythrocytes didn't influence on the leukocyte filtration in blood.

[Changes in rheological properties of blood in multiple sclerosis and their correction].

As many as 45 patients with multiple sclerosis were examined for rheological blood properties. As compared to controls, the group under examination manifested the rise of plasma viscosity, acceleration of red blood cell aggregation. 26.

[The filterability of whole blood (the role of leukocytes and erythrocytes)].

Filterability of the blood with various red cell and leukocyte concentrations was examined in 17 patients with coronary heart disease. The blood was filtered through a filter with pore diameter of 5 microns under a pressure of 100 cm water column. Blood filterability drastically deteriorated if leukocyte concentrations in the blood increased and depended on the leukocyte filtration characteristics.

[Interrelation of the rheological properties of the blood and the state of central hemodynamics in patients with a stable form of hypertension].

A study of 44 patients with second-stage essential hypertension (15 males and 29 females) demonstrated a significant positive correlation between packed cell volume and mean arterial BP (r = 0.794; p less than 0.001), packed cell volume and total peripheral resistance (r = 0.

[Erythrocyte filterability of angina patients].

Erythrocyte filterability and its relation to erythrocyte volume, hemoglobin level and cholesterol/phospholipid ratio were studied in anginal patients. A 25% decrease in filterability and elevated erythrocyte cholesterol/phospholipid ratios were found in anginal patients, as compared to normal subjects. A close inverse correlation (r = -0.

[Role of erythrocyte membrane cholesterol in disorders of their structuro-functional status in patients with ischemic heart disease].

Increased molar cholesterol/phospholipid ratios, significantly increased membrane microviscosity, reduced filterability through a 3 micron-pore filter, increased aggregation and longer disaggregation time, and occasional abnormally large cells were found in erythrocyte assays of 80 coronary patients, as compared to normal subjects. It is suggested that erythrocyte microrheologic disorders are related to excessive cellular cholesterol content in coronary patients.

[Role of the cholesterol of platelet membranes in disorders of their structuro-functional condition in angina pectoris patients].

A study of 80 anginal patients showed their platelet molar cholesterol/phospholipid ratios, platelet membrane microviscosity, membrane release of calcium and fatty acids, and platelet aggregation capacity to be elevated. It is assumed that excessive platelet cholesterol has a significant effect on platelet aggregation, that is mediated by the intraplatelet processes examined, in anginal patients.

[Structural and functional properties of the thrombocytes in ischemic heart disease].

Electronic paramagnetic resonance was used to study the structural and functional properties of platelets from patients with coronary heart disease. It was established with the use of the spin probe 5-doxylstearate that cytoplasmic platelet membranes of coronary heart disease patients are marked by a higher molecular packing as compared to normal. The rate of platelet aggregation studied independently of plasma factors appeared also higher, with a direct correlation being discovered between the aggregation properties and viscosity of platelet membranes.