The relationship between congenital cleft lip and palate malformation, skeletal and dental occlusal anomalies, and the influence of its treatment on affected patients' oral health-related quality of life (OHRQoL).

Objective: Non-syndromic (N/S) cleft lip and/or palate is the most common congenital anomaly to undergo long multidisciplinary treatment. This study investigates patients living with orofacial anomaly and having prolonged treatment by evaluating OHRQoL. It is essential to understand its influence on affected patients' daily life to prepare the most appropriate care for the complete physical, mental, and social well-being of an individual.