Publications by authors named "Reda Amezrou"

Article Synopsis
  • Understanding the genetic basis of how pathogens affect plants is critical for managing fungal diseases, particularly in the context of quantitative traits rather than just strong resistance.
  • Using the Zymoseptoria tritici-wheat model, researchers identified 19 key genes linked to quantitative pathogenicity through a comprehensive genome-wide association study.
  • The study reveals that genetic diversity, driven by sequence changes and recombination, plays a significant role in how pathogens adapt and affect plants, emphasizing the importance of certain genes in influencing pathogenic traits.
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Septoria leaf blotch is a foliar wheat disease controlled by a combination of plant genetic resistances and fungicides use. gene-based qualitative resistance durability is limited due to gene-for-gene interactions with fungal avirulence () genes. Quantitative resistance is considered more durable but the mechanisms involved are not well documented.

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Zymoseptoria tritici is the fungal pathogen responsible for Septoria tritici blotch on wheat. Disease outcome in this pathosystem is partly determined by isolate-specific resistance, where wheat resistance genes recognize specific fungal factors triggering an immune response. Despite the large number of known wheat resistance genes, fungal molecular determinants involved in such cultivar-specific resistance remain largely unknown.

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Crop pathogens pose severe risks to global food production due to the rapid rise of resistance to pesticides and host resistance breakdowns. Predicting future risks requires monitoring tools to identify changes in the genetic composition of pathogen populations. Here we report the design of a microfluidics-based amplicon sequencing assay to multiplex 798 loci targeting virulence and fungicide resistance genes, and randomly selected genome-wide markers for the fungal pathogen Zymoseptoria tritici.

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