In Vivo Characterization of a Wireless Telemetry Module for a Capsule Endoscopy System Utilizing a Conformal Antenna.

This paper describes the design, fabrication, packaging, and performance characterization of a conformal helix antenna created on the outside of a capsule endoscope designed to operate at a carrier frequency of 433 MHz within human tissue. Wireless data transfer was established between the integrated capsule system and an external receiver. The telemetry system was tested within a tissue phantom and in vivo porcine models.

Prognostic monitoring of aircraft wiring using electrical capacitive tomography.

Electrical capacitive tomography (ECT) has been used to monitor sections of aircraft wiring, as a tool for prognostic analysis. To apply the principles of ECT across a cross section of only 4 mm, modification of the basic circuit was required. Additionally, a more novel method of placing the necessary electrodes was needed, this being accomplished by etching them from flexible copper sheeting and wrapping them inside the perimeter of an enclosure.

Data recovery from reduced electrode connection in electrical impedance tomography.

In electrical impedance tomography, a single channel failure causes distortion to the overall image. Mathematical modelling and curve-fitting techniques were used to recover corrupted data. A single channel was disconnected in two experiments on a saline-filled dish with one and two objects, respectively.

Improved potency assay for recombinant bovine somatotropin by high-performance size-exclusion chromatography.

A high-performance size-exclusion chromatographic method was developed for the determination of potency of recombinant bovine somatotropin (rbST) monomer and the estimation of dimer and soluble aggregates in bulk drug substances. These proteins can be completely extracted from bulk drug substances with sodium borate-ethylenediamine-tetraacetic acid disodium salt (EDTA) at pH 9.5 and separated on TSK G3000SW column with a mobile phase of pH 7.

Feasibility of neonatal lung imaging using electrical impedance tomography.

The feasibility of detecting the lungs in preterm babies using electrical impedance tomography (EIT) was investigated. A single frequency instrument using 16 electrodes to apply current and detect peripheral voltages was constructed. The instrument applied AC current of 1.

Conducting boundary strategy: a new technique for medical EIT.

A medical application of a new measurement strategy developed for process tomography is presented. By exchanging the current streamlines with the equipotential lines impedance tomography can be performed using unipolar measurements. The equipotential lines are now parallel to the conducting boundary and voltage measurement is made between this boundary and an insulated electrode.

Single-plane multifrequency electrical impedance instrumentation.

When tissue interacts with electromagnetic radiation it exhibits resistivity and permittivity changes, which decrease with frequency. Above 100 kHz it is expected that dielectric changes in tissue (permittivity) will allow one to distinguish damaged and necrotic tissue. Furthermore, tissue impedance at medium frequencies (100 kHz-1 MHz) have not been well characterized.

Multifrequency electrical impedance tomography.

Multifrequency tomography may be conveniently achieved by sequentially sweeping the probing drive current and measuring the resultant voltages at each frequency. If events change during measurement comparisons between frequencies cannot be made. Mixing several frequency components may decrease acquisition time but increase the complexity of the instrumentation.

Raw data interchange format for electrical impedance tomography.

A data interchange format is described to allow groups working on electrical impedance tomography (EIT) with disparate algorithms and instruments to compare results. The procedure has been tested by exchanging data by e-mail. The format is defined in the appendix.

Electrical impedance tomography. A sensitivity region reconstruction algorithm using adjacent drive current injection strategy.

The 'sensitivity region' method of back projection is converted from polar drive to adjacent drive current injection strategy and individual sensitivity coefficients incorporated. For each projection sensitivity coefficients for each pixel were established and pixels were grouped together into the 'sensitivity regions'. These contain all pixels that have their largest sensitivity coefficients associated with a particular measurement pair.

Neurosurgical stimulation, impedance monitoring and data acquisition system.

We describe the design of a programmable neurosurgical stimulator with impedance monitoring facilities. The computer is used both to control a stimulator and for the storage of various parameters employed in the process. The stimulator is designed to minimize tissue damage by injecting net zero charge; its output is a current, independent of load resistance.

An electronically controlled micro-welder.

An electronically controlled micro-welding apparatus has been designed and built for the manufacture of clinical electrodes. Using the principle of electrical resistance welding, the device is simple and inexpensive to construct, using readily available components. It is easy to operate and has proved to be a quick and reliable method of producing electrodes to the exact specifications of neurosurgeons.