Publications by authors named "Rebekkah Varjabedian"
Article Synopsis
- Pediatric osteoarticular infections are often caused by Staphylococcus aureus, but research on how its genetic variations impact these infections is limited.
- A study of 47 children with either skin colonization or infections involved whole genome sequencing and investigation of virulence genes, indicating that osteoarticular infections carry more immune evasion genes.
- The findings suggest significant genetic diversity in S. aureus strains causing these infections, but no dominant sequence types, and imply that pathogenicity may rely more on gene expression rather than mutations.
Article Synopsis
- - The study examines the impact of respiratory syncytial virus (RSV) in infants under one year old across different healthcare settings, focusing on outpatient (OP) and emergency department (ED) scenarios, which are less explored compared to inpatient (IP) cases.
- - Researchers analyzed data from 627 infants with respiratory symptoms, finding that 28% were RSV-positive, with a median age of 4.5 months; most had no premature birth or significant medical conditions but were more likely to experience lower respiratory tract infections.
- - The findings highlight that RSV-positive infants have varied clinical profiles based on where they seek treatment, indicating that prevention efforts should address different healthcare environments.
Background: The COVID-19 pandemic has presented significant safety concerns for healthcare providers, especially those performing aerosol-generating procedures. Several surgical societies issued early warnings that aerosols generated during minimally invasive surgery (MIS) could harbor infectious quantities of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). This study tested the hypothesis that MIS-aerosols contain SARS-CoV-2.
View Article and Find Full Text PDFBackground: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with increased morbidity and mortality in solid organ transplant (SOT) recipients. Despite exclusion from SARS-CoV-2 vaccine clinical trials, these individuals were identified as high-risk and prioritized for vaccination in public health guidelines.
Methods: We prospectively evaluated humoral and cellular immune responses to two doses of the SARS-CoV-2 mRNA vaccine, BNT162b2, in 56 SOT recipients and 26 healthy controls (HCs).
Objectives: We aimed to evaluate the distribution, clinical presentations and severity of common acute respiratory infections (ARI) viruses in infants across 3 clinical settings.
Study Design: In a prospective virus surveillance study, infants under 1 year with fever and/or respiratory symptoms were enrolled from outpatient, emergency department, and inpatient settings from December 16, 2019 through April 30, 2020. Demographic and clinical characteristics were collected through parent/guardian interviews, medical chart abstractions, and follow-up surveys.