Tic modulation using sensory tricks.

Background: A sensory trick, or geste antagoniste, is defined as a physical gesture (such as a touch on a particular body part) that mitigates the production of an involuntary movement. This phenomenon is most commonly described as a feature of dystonia. Here we present a case of successful modulation of tics using sensory tricks.

Association of glucocerebrosidase mutations with dementia with lewy bodies.

Background: Mutations in the glucocerebrosidase (GBA) gene are associated with Lewy body (LB) disorders.

Objective: To determine the relationship of GBA mutations and APOE4 genotype to LB and Alzheimer disease (AD) pathological findings.

Design: Case-control study.