Exploring the Thioredoxin System as a Therapeutic Target in Cancer: Mechanisms and Implications.

Cells constantly face the challenge of managing oxidants. In aerobic organisms, oxygen (O) is used for energy production, generating reactive oxygen species (ROS) as byproducts of enzymatic reactions. To protect against oxidative damage, cells possess an intricate system of redox scavengers and antioxidant enzymes, collectively forming the antioxidant defense system.