Publications by authors named "Rebecca N Meier"
Article Synopsis
- Transfer of electrophilic alkoxyl groups from tetrahydropyranyl monoperoxyacetals to organometallic reagents allows for efficient ether production, overcoming previous challenges with peroxide stability.
- The method yields a variety of ethers, including alkyl, alkenyl, and aryl types, and operates without generating alkoxy radical intermediates, unlike traditional peroxide reactions.
- Theoretical analysis indicates that the reaction mechanism likely involves a Lewis acid facilitating the insertion of organometallics into the O-O bond, rather than a straightforward nucleophilic substitution (SN2) process.
