Introduction: The U.S. has a higher adolescent pregnancy rate than other industrialized countries.
View Article and Find Full Text PDFWe report a complete 3D structural model of typical epithelial primary cilia based on structural maps of full-length primary cilia obtained by serial section electron tomography. Our data demonstrate the architecture of primary cilia differs extensively from the commonly acknowledged 9+0 paradigm. The axoneme structure is relatively stable but gradually evolves from base to tip with a decreasing number of microtubule complexes (MtCs) and a reducing diameter.
View Article and Find Full Text PDFEukaryotic motile cilia/flagella play vital roles in various physiological processes in mammals and some protists. Defects in cilia formation underlie multiple human disorders, known as ciliopathies. The detailed processes of cilia growth and development are still far from clear despite extensive studies.
View Article and Find Full Text PDFThe author writes a poignant "open" letter to her daughter about her experience with breast cancer, the family legacy of breast cancer, and the impact of learning there is a BRCA1 mutation in the family.
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