Publications by authors named "Rebecca K Ogembo"
Screening for cervical cancer among HIV-positive and HIV-negative women in Cameroon using simultaneous co-testing with careHPV DNA testing and visual inspection enhanced by digital cervicography: Findings of initial screening and one-year follow-up.
Preetam Cholli Leslie Bradford Simon Manga Kathleen Nulah Edith Kiyang Rebecca K Ogembo Javier Gordon Ogembo
Gynecol Oncol
January 2018
Article Synopsis
- - The study evaluated a "screen-and-treat" strategy for cervical cancer screening in HIV-positive and HIV-negative women in Cameroon, using visual inspections and a high-risk HPV test, with a focus on assessing its feasibility and outcomes over a year.
- - Out of 913 women screened, 5% tested positive for visual inspection, but half of those were false positives, highlighting the need for careful triage to avoid unnecessary treatments, especially as HIV-positive women showed a higher likelihood of having HR-HPV.
- - After a year, nearly half of the women who initially tested HR-HPV-positive cleared the infection, with those living with HIV showing a much higher persistence of infection, suggesting different follow-up protocols may be
Background: Several meta-analyses confirmed the five most prevalent human papillomavirus (HPV) strains in women with and without cervical neoplastic diseases are HPV16, 18, 31, 52, and 58. HPV16/18 are the predominant oncogenic genotypes, causing approximately 70% of global cervical cancer cases. The vast majority of the women studied in previous analyses were from Europe, North America, Asia, and most recently Latin America and the Caribbean.
View Article and Find Full Text PDF