Publications by authors named "Rebecca J Lodge"
Article Synopsis
- The study focuses on the role of the CSF1R receptor in the development and survival of mononuclear phagocytes (macrophages) in mammals.
- Researchers found that deleting a specific regulatory element, FIRE, in mice reduced CSF1R expression and disrupted macrophage development in certain tissues, leading to a lack of macrophages in various areas such as the brain and skin.
- Despite these changes, the mice appeared healthy and did not show any major developmental or neurological issues, making them useful for studying the functions of specific macrophage populations in adults.
