Publications by authors named "Rebecca Falender"

We evaluated the association between wastewater concentration and weekly percent positivity of patient testing for SARS-CoV-2, influenza, and respiratory syncytial virus in Oregon, USA. We found strong, positive correlations for SARS-CoV-2 (ρ = 0.84, p<0.

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Article Synopsis
  • * From May 12 to July 13, 2024, 38 states participated in testing, with 11 sites showing high levels of influenza A virus and 24 sites detecting the H5 subtype.
  • * Investigations revealed that many high-level detections corresponded with human influenza activity and identified possible animal sources, providing valuable data for future respiratory illness monitoring.
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Cryptosporidium poses significant public health risks as a cause of waterborne disease worldwide. Clinical surveillance of cryptosporidiosis is largely underreported due to the asymptomatic and mildly symptomatic infections, clinical misdiagnoses, and barriers to access testing. Wastewater surveillance overcomes these limitations and could serve as an effective tool for identifying cryptosporidiosis at the population level.

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We estimated SARS-CoV-2 seroprevalence in children in Oregon, USA, at 6 time points. Seroprevalence increased linearly during November 2020-December 2021 and peaked in February 2022 at 38.8% (95% CI 32.

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Article Synopsis
  • Reinfections of SARS-CoV-2 in the U.S. have become more common, especially during the Omicron variant period, rising from 2.7% during Delta to 28.8% in Omicron BQ.1/BQ.1.1.
  • Hospitalizations and deaths linked to reinfections also increased significantly, going from 1.9% and 1.2% of COVID-19-related cases during Delta, to 17.0% and 12.3% during Omicron BQ.1/BQ.1.1.
  • Younger adults (18-49 years) had higher rates of reinfections compared to older adults (≥50 years), and it's crucial to stay updated on vaccinations
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SARS-CoV-2 variant proportions in a population can be estimated through genomic sequencing of clinical specimens or wastewater samples. We demonstrate strong pairwise correlation between statewide variant estimates in Oregon, USA, derived from both methods (correlation coefficient 0.97).

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