Publications by authors named "Rebecca Butfield"

Aims: Reporting of hospitalization cost data for the National Health Service in England evolved substantially in the past decades which may have led to inconsistency in capturing the average cost of hospitalizations in appraisals of new health technologies. Our aim was to systematically review the estimation of hospitalization costs in appraisals for the National Institute for Health and Care Excellence (NICE) and the Joint Committee on Vaccination and Immunisation (JCVI), to identify potential heterogeneity and its drivers. A case study was used to explore the impact of alternative cost estimates on economic evaluations.

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Background: Updating vaccines is essential for combatting emerging coronavirus disease 2019 (COVID-19) variants. This study assessed the public health and economic impact of a booster dose of an adapted vaccine in the United Kingdom (UK).

Methods: A Markov-decision tree model estimated the outcomes of vaccination strategies targeting various age and risk groups in the UK.

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Article Synopsis
  • * Using an SEIR model, researchers assessed various vaccination strategies, concluding that the autumn 2022/spring 2023 booster campaign significantly reduced hospitalizations by 18,921 and deaths by 1,463 compared to not having a booster program.
  • * Expanding booster eligibility and increasing uptake further improved health outcomes, yielding twice as many averted ICU admissions and reducing long COVID cases, while also minimizing lost productive days by fivefold.
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Article Synopsis
  • The study aimed to analyze the direct costs and healthcare resource usage associated with acute COVID-19 in adults in England during a specific timeframe.
  • It included over 1.7 million adults who tested positive for COVID-19, focusing on hospitalizations and primary care interactions, particularly in older and immunocompromised individuals.
  • Findings revealed that older adults had longer hospital stays and higher median costs compared to younger adults, with increased healthcare utilization among those at higher risk of severe COVID-19.
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Background: Although COVID-19 morbidity is significantly lower in pediatrics than in adults, the risk of severe COVID-19 may still pose substantial health care resource burden. This study aimed to describe health care resource utilization (HCRU) and costs associated with COVID-19 in pediatrics 1-17 years old in England.

Methods: A population-based retrospective cohort study of pediatrics with COVID-19 using Clinical Practice Research Datalink (CPRD Aurum) primary care data and, where available, linked Hospital Episode Statistics Admitted Patient Care secondary care data.

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