Aims: Reporting of hospitalization cost data for the National Health Service in England evolved substantially in the past decades which may have led to inconsistency in capturing the average cost of hospitalizations in appraisals of new health technologies. Our aim was to systematically review the estimation of hospitalization costs in appraisals for the National Institute for Health and Care Excellence (NICE) and the Joint Committee on Vaccination and Immunisation (JCVI), to identify potential heterogeneity and its drivers. A case study was used to explore the impact of alternative cost estimates on economic evaluations.
View Article and Find Full Text PDFBackground: Updating vaccines is essential for combatting emerging coronavirus disease 2019 (COVID-19) variants. This study assessed the public health and economic impact of a booster dose of an adapted vaccine in the United Kingdom (UK).
Methods: A Markov-decision tree model estimated the outcomes of vaccination strategies targeting various age and risk groups in the UK.
Background: Although COVID-19 morbidity is significantly lower in pediatrics than in adults, the risk of severe COVID-19 may still pose substantial health care resource burden. This study aimed to describe health care resource utilization (HCRU) and costs associated with COVID-19 in pediatrics 1-17 years old in England.
Methods: A population-based retrospective cohort study of pediatrics with COVID-19 using Clinical Practice Research Datalink (CPRD Aurum) primary care data and, where available, linked Hospital Episode Statistics Admitted Patient Care secondary care data.