Publications by authors named "Rebecca A Greene"

Purpose: To describe the pharmacokinetics of flucytosine in a critically ill patient undergoing continuous venovenous hemodiafiltration (CVVHDF) treated for cryptococcal meningitis.

Summary: A 20-year-old female weighing 93.4 kg with a body mass index of 34.

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Objectives: To determine whether best practice advisories improved sedation protocol compliance and could mitigate potential propofol-related hazardous conditions.

Design: Retrospective observational cohort study.

Setting: Two adult ICUs at two academic medical centers that share the same sedation protocol.

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Article Synopsis
  • Antithrombin III deficiency during extracorporeal membrane oxygenation (ECMO) can lead to heparin resistance; however, supplementation may help improve anticoagulation.
  • A study analyzed the effects of antithrombin III supplementation on coagulation parameters in both adult and pediatric ECMO patients.
  • Results indicated that while antithrombin III improved anti-Xa levels significantly, it did not substantially decrease heparin infusion rates, suggesting restoration of heparin responsiveness in patients with low antithrombin activity.
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