Publications by authors named "Re-Ai-La Jianati"
[Inhibitory Effect of Cinobufotalin on Macrophage Inflammatory Factor Storm and Its Mechanism].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
June 2023
Article Synopsis
- The study aimed to explore how Cinobufotalin affects inflammation in monocytes and activated macrophages, investigating its molecular mechanisms.* -
- THP-1 cells were used to create macrophage activation models, and Cinobufotalin treatment showed a significant reduction in cell proliferation and increased apoptosis, especially in activated macrophages.* -
- Cinobufotalin's anti-inflammatory effects were linked to the inhibition of the TLR4/MYD88/P-IκBa signaling pathway, suggesting its potential for treating diseases related to excessive inflammation.*