Publications by authors named "Raziyeh Asadi"
Article Synopsis
- The low oral bioavailability of selegiline hydrochloride is caused by extensive first-pass metabolism, leading to the exploration of sublingual films as an alternative delivery method.
- Various formulations of sublingual films (F1-F6) were tested for their physical and chemical properties, with film F2 showing promising characteristics such as good weight, folding endurance, and mucoadhesive strength.
- The sublingual flux of the SH film was higher than that of the plain drug, indicating that sublingual delivery could enhance the effectiveness of selegiline hydrochloride.
