[Post-malaria neurological syndrome complicating a Plasmodium falciparum malaria in Madagascar].

Post-malaria neurological syndrome is a rare complication of malaria. Typically, it occurs in case of severe malaria. Here we report a case in a Malagasy patient presenting a non-severe Plasmodium falciparum malaria complicated by post-malaria neurological syndrome.

[Premature deliveries at the maternity hospital of Befelatanana, Antananarivo in 1997].

Preterm deliveries (PT) produce new-borns whose prognosis is generally very dark. Prematurity is the first cause of neonatal death. A retrospective study was carried out at the Maternity Hospital of Befelatanana, Antananarivo in order to specify causes and difficulties of PT and to draw up strategy for their better management so that premature infants have chance to survive.

[Pseudo-poliomyelitis paralysis caused by Echovirus 7].

The authors describe one case of acute flaccid paralytic of lower limbs in a 10-year-old boy with Echovirus 7 isolated in the stool and a high titer of homologous antibodies (> or = 1,024). At the final stage of poliomyelitis program eradication, paralysis associated with non polio enterovirus may replace cases of paralytic poliomyelitis. In the present study, the authors highlight the needs to confirm virologically all suspect cases of acute flaccid paralytic.

[Severe malaria in children at the pediatric service of the Befelatanana Hospital Center at Antananarivo (Madagascar) in 1996-1998].

The definition of severe malaria is no longer limited to cerebral malaria, but it is as well extended to other clinical forms of the disease. The authors reported the epidemiological and clinical survey and evaluative aspects of severe malaria in Antananarivo. This retrospective study included 48 children less than 15 years old, hospitalized at the paediatric unit Debré of the Centre Hospitalier Universitaire de Befelatanana (Antananarivo) for severe malaria as defined by world Health Organization (WHO) criteria.

[The malaria epidemic in Antananarivo from 1983 to 1994 as seen through the Pediatric Service A in the Befelatanana General Hospital].

We report the symptoms of children affected by an epidemy of a serious form of malaria which raged in Tananarive from 1983 to 1994. These data are based on the hospital registers for the "Debré" room of the Pediatric Service "A" in the Befelatanana Hospital, and underline a few points as follows. In terms of morbidity, the epidemy started in 1984, reached a peak in 1988 (26.

Parasite virulence factors during falciparum malaria: rosetting, cytoadherence, and modulation of cytoadherence by cytokines.

To determine virulence factors of isolates of Plasmodium falciparum and the potential role of cytokines in cerebral malaria, 46 Malagasy patients presenting with cerebral (n = 10), severe (n = 10), and uncomplicated (n = 26) malaria were enrolled in a study. The capacity of 21 of 46 P. falciparum isolates to form rosettes in vitro and to adhere to human umbilical vein endothelial cells (HUVECs) that express intercellular adhesion molecule-1 receptors and to C32 amelanotic melanoma cells that express mainly CD36 receptors was investigated together with the effects of tumor necrosis factor alpha (TNF-alpha), granulocyte macrophage-colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-6 alone and in two-by-two combinations on the cytoadherence of infected erythrocytes to HUVECs.

[Oral rice-based rehydration solution (SRO), alternative of SRO of WHO in acute diarrhea in malnourished patients].

Background: Although malnutrition is frequently associated with diarrhea, most oral rehydration solutions have been tested in well-nourished children. The study tests efficacy of rice, a traditional treatment for diarrhea in Madagascar.

Patients And Methods: 150 severely malnourished children, aged 6 months to 3 years, took part in this randomized trial.

[Epidemiological data on children hospitalized with malaria from 1983 to 1992].

Authors record the manifestations on the child of the severe malaria epidemic that raged in Antananarivo. Using the hospitalisation registers of the Debré room, Pediatric Service "A", at the Hospital of Befelatanana as source documents, they underline some points: Concerning morbidity, the epidemic started in 1984, reached its highest point in 1988 (26.7%, of in patients) and began to fade away in 1992.

[Infantile diarrheal diseases in Madagascar: bacterial, parasitologic and viral study].

From November 1988 to October 1989, an etiological study showed off the prevalence and the part of several enteropathogen agents which are not yet studied in MADAGASCAR. 1,523 stool's samples from 884 children with diarrhea and 639 children without diarrhea from 0 to 14 years old have been investigated. A bacterial, parasitical or viral etiology was found from 36.

The malaria epidemic in Antananarivo observed from Pediatric Service "A" of the Befelatanana General Hospital.

A recent malaria epidemic striking Antananarivo, the capital city of Madagascar, is shown from hospital records of Pediatric Service "A" of the Befelatanana General Hospital. From 1980 to 1988 malaria cases in this hospital service increased from 0.9% to 14.

[Viral etiology of acute respiratory infections in Madagascan children].

A total of 80 nasopharyngeal secretions collected from malagasy children (53 boys and 27 girls) with viral acute respiratory infection, aged from 6 days to 10 year old admitted to the Pediatric Department of Antananarivo General Hospital from may to July 1983, were investigated by indirect immunofluorescence method. 54--samples were found positive for respiratory viruses. Distribution according age groups and sex has been studied: children belonging to 25-36 month age group and male sex were more infected.