Exploring the Therapeutic Potentials and Molecular Mechanisms of Alkaloids in Ulcerative Colitis: An Integrative Network Pharmacology and Molecular Docking Approach.

, a medicinal plant traditionally used in Southeast Asia, exerts protective effects against various inflammatory diseases, primarily due to its rich alkaloid content. Despite substantial evidence supporting its anti-inflammatory properties, the biological activities of are unclear. This study aimed to elucidate anticolitis mechanisms of alkaloids (CFAs) using an integrative approach of network pharmacology and molecular docking analyses.

Antioxidant and Anti-Inflammatory Mechanisms of Lipophilic Fractions from Leaves Based on Network Pharmacology, In Silico, and In Vitro Approaches.

leaf (PFL) has been used in food and traditional medicine for the treatment of rheumatism, ischemia, and neuralgia. However, the lipophilic components of PFL and their biological properties remain unknown. This study, integrating network pharmacology analysis with in silico and in vitro approaches, aimed to elucidate the antioxidant and anti-inflammatory capacities of lipophilic extracts from PFL.

Anti-Inflammatory and Antioxidant Activities of Lipophilic Fraction from Seeds Using Network Pharmacology, Molecular Docking, and In Vitro Experiments.

Antioxidant and anti-inflammatory mechanisms counteract the pathogenesis of chronic diseases, such as diabetes, aging, and cancer. Therefore, enhancing antioxidant and anti-inflammatory functions may help manage these pathological conditions. This study aimed to assess the antioxidant and anti-inflammatory potentials of lipophilic fraction of seeds (LLPS) using network pharmacology, molecular docking, and in vitro experiments.

Red ginseng dietary fiber promotes probiotic properties of and alters bacterial metabolism.

Korean red ginseng has been widely used as an herbal medicine. Red ginseng dietary fiber (RGDF) is a residue of the processed ginseng product but still contains bioactive constituents that can be applied as prebiotics. In this study, we evaluated changes on fermentation profiles and probiotic properties of strains that belong to family with RGDF supplementation.

Protective Effects of Orange Sweet Pepper Juices Prepared by High-Speed Blender and Low-Speed Masticating Juicer against UVB-induced Skin Damage in SKH-1 Hairless Mice.

Sweet pepper fruits ( L.) contain various nutrients and phytochemicals that enhance human health and prevent the pathogenesis of certain diseases. Here, we report that oral administration of orange sweet pepper juices prepared by a high-speed blender and low-speed masticating juicer reduces UVB-induced skin damage in SKH-1 hairless mice.