On in-silico estimation of left ventricular end-diastolic pressure from cardiac strains.

Left ventricular diastolic dysfunction (LVDD) is a group of diseases that adversely affect the passive phase of the cardiac cycle and can lead to heart failure. While left ventricular end-diastolic pressure (LVEDP) is a valuable prognostic measure in LVDD patients, traditional invasive methods of measuring LVEDP present risks and limitations, highlighting the need for alternative approaches. This paper investigates the possibility of measuring LVEDP non-invasively using inverse in-silico modeling.