Publications by authors named "Raza R Rahman"
Background: A third of patients diagnosed with major depressive disorder (MDD) experience treatment-resistant depression (TRD). Relatively few pharmacological agents have established efficacy for TRD. Therefore, the evaluation of novel treatments for TRD is a pressing priority.
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- A study investigated the effects of minocycline, an anti-inflammatory medication, on patients with treatment-resistant depression when added to standard treatment over 3 months.
- The trial was double-blind and placebo-controlled, involving 41 participants, with significant improvements in depressive symptoms (measured by HAMD scores) observed in those receiving minocycline compared to the placebo group.
- The results suggest minocycline may help alleviate treatment-resistant depression symptoms, but further research is needed with a larger group to confirm these findings.*
Background: Despite the use of maintenance medication, recurrence rates in bipolar affective disorder (BPAD) are high. To date, there are no clinical trials that have investigated the use of psychological interventions in bipolar disorder in Pakistan.
Aim: The purpose of the study was to assess the feasibility and acceptability of a culturally adapted bipolar psychoeducation programme (CaPE) in Pakistan.
Background: Depression is one of the leading causes of disability worldwide. A high proportion of patients do not respond to standard drug treatments. Recent evidence has suggested that anti-inflammatory treatment may have beneficial effects in major depression.
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