Publications by authors named "Raza Hassan"

This paper investigates the behavior of fractional-order nonlinear multi-agent systems subjected to Byzantine assaults, specifically focusing on the manipulations of both sensors and actuators. We employ weighted graphs, both directed and undirected, to illustrate the system's topology. Our methodology combines algebraic graph theory with fractional-order Lyapunov techniques to develop algebraic requirements for leader-following consensus, providing a robust framework for analyzing consensus dynamics in these complex systems.

View Article and Find Full Text PDF

Within the intricate fabric of human physiology, cholesterol, a lipid present in cell membranes exerts a discernible effect on the concentration of the drug in human body that influence the aspects of drug pharmacokinetics. The objective of this work is to design a case study based fractional order cholesterol drug interaction model that encapsulates the nuanced dynamics inherent in the multifaceted human physiology with identification of essential variables including drug concentration K and cholesterol level γ. The strength of nonlinear autoregressive with exogenous inputs (NARX) neural networks are exploited to predict the temporal dynamics that reveal the hidden intricacies and subtle patterns within the fractional model.

View Article and Find Full Text PDF

This study evaluated the anti-oxidant and anti-diabetic potential of (CF) in 28-days rat modelling trial. Diabetes is a chronic disorder characterized by elevated blood glucose levels and insulin resistance and cause microvascular and macrovascular issues. was evaluated for its nutritional composition along with anti-oxidant potential of CF powder (CFP) and CF extract (CFE) using total phenolic contents (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric ion reducing antioxidant power (FRAP) assays.

View Article and Find Full Text PDF

This paper examines the impact of the Monetary Policy Uncertainty (MPU) of the United States on Asian developed, emerging, and frontier stock markets using a Quantile-on-Quantile (QQR) approach by using monthly data from January 2006 to December 2022 of 14 Asian countries. The study finds that US monetary policy significantly negatively influences Asian stock markets. This is primarily due to the widespread use of the US dollar as a universal currency, resulting in substantial ripple effects on other nations through trade relationships.

View Article and Find Full Text PDF

The growing demand for biological therapeutics has increased interest in large-volume perfusion bioreactors, but the operation and scalability of perfusion membranes remain a challenge. This study evaluates perfusion cell culture performance and monoclonal antibody (mAb) productivity at various membrane fluxes (1.5-5 LMH), utilizing polyvinylidene difluoride (PVDF), polyethersulfone (PES), or polysulfone (PS) membranes in tangential flow filtration mode.

View Article and Find Full Text PDF

The diversity in the global food market is expanding as thousands of new products enter the business every year, among which nutraceutical and functional foods hold important positions. The present research work aimed at the nutritional evaluation of three medicinal herbs, i.e.

View Article and Find Full Text PDF

Hollow fiber filter fouling is a common issue plaguing perfusion production process for biologics therapeutics, but the nature of filter foulant has been elusive. Here we studied cell culture materials especially Chinese hamster ovary (CHO) cell-derived extracellular vesicles in perfusion process to determine their role in filter fouling. We found that the decrease of CHO-derived small extracellular vesicles (sEVs) with 50-200 nm in diameter in perfusion permeates always preceded the increase in transmembrane pressure (TMP) and subsequent decrease in product sieving, suggesting that sEVs might have been retained inside filters and contributed to filter fouling.

View Article and Find Full Text PDF

Background: Urinary bladder tumor recurrence following transurethral resection of bladder tumor (TURBT) is a common issue. This study aims to determine how urine alkalinization affects bladder tumor recurrence after surgery.

Materials And Methods: Sixty patients receiving mitomycin C (MMC) therapy after TURBT were divided into two groups based on mean pH values.

View Article and Find Full Text PDF

Purpose: To assess skin-to-skin contact during cesarean birth, including incidence and maternal characteristics.

Study Design And Methods: A cross-sectional, retrospective study using survey methods was conducted. Women who had a cesarean birth within the last 10 years prior to January 2022 were recruited via social media.

View Article and Find Full Text PDF

Anticoagulation is mainstay therapy for patients with acute pulmonary embolism while systemic thrombolysis is reserved for those with hemodynamic instability. Over the last decade, percutaneous interventional options have entered the landscape aimed to achieve rapid pharmacomechanical pulmonary artery recanalization. The Penumbra Indigo Aspiration System (Penumbra Inc.

View Article and Find Full Text PDF

Fibrodysplasia ossificans progressiva (FOP), also known as Stoneman syndrome, is a rare genetic disorder characterized by abnormal bone development caused by activating mutations of the gene. FOP affects both the developmental and postnatal stages, resulting in musculoskeletal abnormalities and heterotopic ossification. Current treatment options for FOP are limited, emphasizing the need for innovative therapeutic approaches.

View Article and Find Full Text PDF

Rapid advances in the engineering application prospects of metal-organic framework (MOF) materials necessitate an urgent in-depth understanding of their mechanical properties. This work demonstrates unprecedented recoverable elastic deformation of Ni-tetraphenylporphyrins (Ni-TCPP) MOF nanobelts with a tensile strain as high as 14%, and a projected yield strength-to-Young's modulus ratio exceeding the theoretical limit (≈10%) for crystalline materials. Based on first-principles simulations, the observed behavior of MOF crystal can be attributed to the mechanical deformation induced conformation transition and the formation of helical configuration of dislocations under high stresses, arising from their organic ligand building blocks in the crystal structures.

View Article and Find Full Text PDF

Currently, the rate of intimate partner violence (IPV) in Pakistan is 29%, which is likely an underestimate. This study used mixed models to examine the effects of women empowerment, women and husband's education, number of adult women in a household, number of children 5 or under in a household, and place of residence on physical violence and controlling behavior, controlling for women's current age and wealth status. Nationally representative data collected from 3,545 currently married women in the Pakistan Demographic and Health Survey (2012-2013) was used for the current study.

View Article and Find Full Text PDF

Introduction The Chughtai Laboratory collects blood samples for complete blood counts from various hospitals, emergency departments, ICUs, and through home sampling services all across the country. The preanalytical phase is an integral component of laboratory medicine. A laboratory report has a key role in patient treatment and the clinician's decision in the management of the disease.

View Article and Find Full Text PDF

Epidermolysis bullosa (EB) is a rare heterogeneous group of diseases which typically presents with extensive blistering and mucocutaneous erosions. EB is mechanobullous in nature and thus commonly involves sites of trauma and friction. It is a painful and disfiguring disorder.

View Article and Find Full Text PDF

Unlabelled: Background Nucleated red blood cells (NRBCs) are not normally found in the peripheral blood of normal healthy individuals. The presence of NRBCs on an adult peripheral blood smear indicates that there is an extremely high demand for the bone marrow to manufacture RBCs and that immature red blood cells are being released into the bloodstream. Anemia, myelofibrosis, thalassemia, miliary tuberculosis, malignancies of the bone marrow (myelomas, leukemias, lymphomas), and prolonged hypoxemia are a few possible pathogenic reasons.

View Article and Find Full Text PDF

Chylous ascites is a rare but significant complication of a variety of surgical procedures. It is an uncommon complication of laparoscopic Roux-en-Y gastric bypass (LRGYB). The underlying etiology is assumed to be an internal hernia, in which the hernia causes lymphatic channel engorgement and lymphatic extravasation.

View Article and Find Full Text PDF
Article Synopsis
  • Hypokalemic periodic paralysis (HPP) involves sudden muscle weakness due to low potassium levels, while thyrotoxic periodic paralysis (TPP) is a specific type associated with hyperthyroidism and requires cautious potassium replacement.
  • A young male with untreated hyperthyroidism experienced sudden weakness in his legs, diagnosed with severe hypokalemia, thyroid issues, and specific ECG changes.
  • After receiving potassium and treatment for his thyroid condition in the ICU, his potassium levels shot up dramatically, leading to a quick recovery of strength and warning against rapid potassium repletion to prevent complications.
View Article and Find Full Text PDF

Psoriasis is chronic autoimmune disease that affects 2-5% of the global population. Fluocinolone acetonide (FLU) and acitretin (ACT) are widely used antipsoriatic drugs that belong to BCS classes II and IV, respectively. FLU exhibits side effects, such as skin irritation and a burning sensation.

View Article and Find Full Text PDF
Article Synopsis
  • Acute appendicitis (AA) is a critical surgical condition that necessitates quick diagnosis and treatment; this study examines the effectiveness of the Alvarado scoring system (ASS) in diagnosing AA based on histopathological outcomes.
  • The study involved 120 patients (96 males and 24 females) aged 20 to 60, assessing their Alvarado score against the gold standard of histopathology, calculating various diagnostic metrics like sensitivity (83.3%) and positive predictive value (PPV) (85%).
  • The Alvarado scoring system is deemed a practical diagnostic method, particularly in developing nations, as it is cost-effective and easy to implement, despite a notable negative appendectomy rate of 21%.
View Article and Find Full Text PDF
Article Synopsis
  • Background: Dyslipidemia is a common but underreported risk factor for ischemic stroke in Pakistan, contributing to high morbidity and an economic burden on society.
  • Methodology: A seven-month study at Shalamar Hospital in Lahore analyzed 104 stroke patients to assess dyslipidemia through blood samples and collected demographic data.
  • Results: The study found that 39.42% of ischemic stroke patients had dyslipidemia, emphasizing the urgent need for awareness and interventions like diet changes and medication to manage this risk factor among the population.
View Article and Find Full Text PDF

The devastating effects of the COVID-19 pandemic have left many repercussions for the tourism industry to preempt any future catastrophe of this nature. The research aims to propose recommendations for the post-COVID-19 business world to revitalize and reclaim their market space and win back their volumes without any fear of indefinite closures and continued lockdowns in the industry. Drawing from the literature, the study assumed revitalization through responsiveness, use of advanced technology, customers' and employees' willingness, enhanced skills, adherence to standard operating procedures and protective measures, and restructuring via a public-private partnership.

View Article and Find Full Text PDF

Objectives: Peripherally inserted central catheters (PICCs) are increasingly recognized as an alternative to centrally inserted central catheters (CICCs) in critical care, yet the data regarding the safety and feasibility of this choice in septic shock management is growing but still lacking. In this study, we aimed to determine the feasibility, safety, and impact on outcomes of using dedicated vascular access specialist (VAS) teams to insert PICCs versus CICCs on patients admitted to the ICU with septic shock.

Design: Retrospective cohort study.

View Article and Find Full Text PDF

The failure or success of an enterprise depends upon its working capital management practices (WCMP) along with effective corporate social responsibilities (CSR) and social entrepreneurship (SE). These factors ensure not only the soundness of financial indicators but also the profitability of an enterprise. Therefore, the objective of this study was to determine the impact of CSR, SE, and WCMP on the performance of small-medium enterprises (SMEs) of tourism sector, during the lockdown period in Malaysia.

View Article and Find Full Text PDF