Publications by authors named "Rayyanoor Jawad"
Alcohol Clin Exp Res
May 2022
Article Synopsis
- Binge alcohol exposure during adolescence causes lasting changes in brain connectivity and behavior, affecting important interneurons in the prefrontal cortex (PFC) and striatum that influence neural functions.
- A study found that while the density of choline acetyltransferase (ChAT) and parvalbumin (PV) interneurons remained similar in AIE-exposed rats compared to controls, the density of extracellular perineuronal nets (PNNs) was significantly greater in AIE rats.
- This suggests that AIE exposure may alter the role of PV interneurons, as more of them were surrounded by PNNs, potentially affecting their functionality in the adult brain.
