Chronic Resistance Training Does Not Ameliorate Unloading-Induced Decrements in Neuromuscular Function.

Objective: The aim of this study was to assess the efficacy of long-term resistance training in preventing the detrimental effects of muscle unloading on neuromuscular function.

Design: Eleven untrained men and 11 men with extensive backgrounds in resistance training were tested for several parameters of neuromuscular function at various isokinetic contractile velocities before and after 7 days of muscle unloading. Measurements included muscle mass, strength, power, total work, electromyography, and neuromuscular transmission efficiency using superimposed electrical stimulation of maximally contracting muscles.

Factors relating to gender specificity of unloading-induced declines in strength.

Introduction: This investigation aimed to: (1) confirm whether women were more vulnerable to the negative neuromuscular adaptations elicited by muscle unloading and if so, (2) determine which physiological mechanism(s) explain those gender-related differences.

Methods: Healthy young men (20.7 ± 0.

Gender influences neuromuscular adaptations to muscle unloading.

Muscle unloading results in decreased strength. This is partly attributed to reduced neural activation. This study examined whether men and women experienced different adaptations to muscle unloading.

The efficacy of prehabilitative conditioning: ameliorating unloading-induced declines in the muscle function of humans.

Objective: To determine whether prehabilitation, or exercise performed before muscle unloading, can effectively mitigate decreases in neuromuscular function typically elicited by unloading.

Design: Ten healthy, untrained young men (20.9 +/- 1.

Adaptations to short-term muscle unloading in young and aged men.

Introduction: The purpose of this investigation was to determine whether young (21.7 yr) and aged (68.5 yr) men experienced similar responses to 7 d of muscle unloading (N = 10 per group).

Neural factors account for strength decrements observed after short-term muscle unloading.

Strength decrements observed after extended (4-6 wk) periods of muscle unloading are associated with significant atrophy. Because early (up to 2 wk) strength gains from resistance exercise are related to improved neural recruitment, we hypothesized that the loss of strength resulting from 2 wk of muscle unloading [unilateral lower limb suspension (ULLS)] was due to impaired neural activation of the affected muscle. Blood samples, muscle biopsy specimens, muscle function data, and electromyography (EMG) recordings were analyzed before and after 14 days of muscle unloading.