Visual field characteristics in neuromyelitis optica in absence of and after one episode of optic neuritis.

Purpose: Optic neuritis (ON) observed during neuromyelitis optica (NMO) is in most cases very severe and with poor prognosis. This study's objective was to analyze visual field (VF) abnormalities observed in the absence of ON and post-ON episode.

Methods: Twenty-seven cases of both NMO and multiple sclerosis (MS) were selected.

Treatment of optic neuritis by plasma exchange (add-on) in neuromyelitis optica.

Objective: To assess the contribution of plasma exchange (PE) in association (add-on) with pulsed intravenous corticosteroids in acute optic neuritis of neuromyelitis optica (NMO) and limited forms of NMO.

Methods: Thirty-six patients with optic neuritis were treated from January 1, 1995, through December 31, 2010, with pulsed intravenous corticosteroids and 16 with pulsed intravenous corticosteroids plus PE. The ophthalmologic examination was performed at least 6 months after optic neuritis treatment.

Anatomic and functional correlation of frequency-doubling technology perimetry (FDTP) in multiple sclerosis.

To study the correlation between the results of frequency-doubling technology perimetry (FDTP), visual function (visual acuity, contrast vision, standard automated perimetry (SAP)) and the thickness of the retinal nerve fiber layer (RNFL) throughout the course of multiple sclerosis (MS). Sixty-six eyes of thirty-three patients suffering from MS were chosen. Thirty-five eyes had a previous history of optic neuritis (ON group) and thirty-one eyes had no previous history of optic neuritis (non-ON group).

[Alternatives to mutilating surgery. ].

Objective: The purpose of this study is to suggest an alternative surgery to mutilating exenteration and enucleation surgeries in the management of nonfunctional, unattractive, and painless eyes. The suggested alternative is lamellar keratectomy with conjunctiva recovery.

Design: Retrospective study.

Retinal nerve fiber layer thickness and spatial and temporal contrast sensitivity in multiple sclerosis.

Purpose: To measure peripapillary retinal nerve fiber layer (RNFL) thickness and spatial and temporal contrast sensitivity in multiple sclerosis (MS) taking into account previous history of optic neuropathy (ON).

Methods: Thirty patients (60 eyes) with relapsing-remitting MS were selected (MS group). The MS ON group was composed of 31 eyes with previous history of optic neuropathy and the MS non-ON group of 29 eyes was without previous history of optic neuropathy.

Retinal peripapillary nerve fiber layer thickness in neuromyelitis optica.

Purpose: To measure the thickness of retinal peripapillary nerve fibers throughout the course of neuromyelitis optica (NMO).

Methods: This study was of a cross-sectional design, examining the thickness of the retinal peripapillary nerve fiber layer by optical coherence tomography, in patients with NMO (n = 15; 30 eyes), patients with multiple sclerosis (MS; n = 15; 30 eyes), and a control group (n = 23; 46 eyes). The thicknesses were acquired according to protocol with the fast RNFL (Retinal Nerve Fiber Layer) procedure.

Familial bilateral polypoidal choroidal vasculopathy.

Purpose: Description of the clinical and angiographic manifestations of polypoidal choroidal vasculopathy (PCV) in two brothers of West Indian origin.

Method: Case reports.

Results: In Case 1 (82-year-old), the disease presented when the patient was 50 years old with decreased visual acuity in the right eye.

Natural history of the visual impairment of relapsing neuromyelitis optica.

Purpose: To describe the clinical features and natural history of the visual impairment of relapsing neuromyelitis optica.

Design: Prospective observational case series.

Participants: Thirty patients of Afro-Caribbean origin with neuromyelitis optica and 47 patients with multiple sclerosis.