Analysis of efficacy and safety of treatment with collagenase Clostridium histolyticum among subgroups of patients with Dupuytren contracture.

Collagenase Clostridium histolyticum (CCH) injection is a nonoperative treatment of hand contractures from Dupuytren disease. This study assessed the efficacy and safety of CCH in several subgroups of patients with increased surgical risk.Data were pooled from 3 randomized, placebo-controlled, double-blind trials.

Guidelines for ethical and professional use of social media in a hand surgery practice.

In growing numbers, patients are using social media platforms as resources to obtain health information and report their experiences in the health care setting. More physicians are making use of these platforms as a means to reach prospective and existing patients, to share information with each other, and to educate the public. In this ever-expanding online dialogue, questions have arisen regarding appropriate conduct of the physician during these interactions.

The extended-short nail system, a novel concept in the management of proximal femur fractures.

In light of recent health care reform and the aging US Medicare population, it is becoming increasingly important for orthopedic surgeons to use effective and efficient strategies for hip fracture surgery. The Extended-Short Nail System (ES nail) is a US Food and Drug Administration-approved titanium nail which is locked at the same location as the locking hole of a short intramedullary (IM) nail. The ES nail takes advantage of an "extended-short" hybrid design combining the mechanical characteristics of a long IM nail with the surgical ease of use offered with a short IM nail.

Nontraumatic, spontaneous dislocation of polyethylene tibial insert 1 year after TKA.

The authors report a case of nontraumatic, spontaneous dislocation of a polyethylene insert detected 1 year after total knee arthroplasty. The patient demonstrated initial improvement and returned to work 4 months postoperatively. At 6 months postoperatively, the patient developed pain and a clunking sensation with motion; however, he denied any traumatic precipitating events.

Extensor mechanism repair failure with use of bidirectional barbed suture in total knee arthroplasty.

Total knee arthroplasty (TKA) continues to advance as innovative devices become available. #2 PDO Quill SRS (Angiotech, Reading, Pa) bidirectional barbed suture was used for 161 primary TKAs at our facility. We report on 3 separate cases of extensor mechanism repair failure after primary TKA in which a barbed suture was used for extensor mechanism closure.

The in vitro elution characteristics of antifungal-loaded PMMA bone cement and calcium sulfate bone substitute.

The use of antimicrobial-loaded delivery vehicles, most often as antibiotic beads, is common practice for the treatment of deep musculoskeletal infections. The elution of antibacterial drugs from various bone cements has been extensively studied. However, much less is known about the elution of other antimicrobials from these materials.