Publications by authors named "Raymond M Khan"
Article Synopsis
- Antibiotic therapy timing is critical in treating sepsis, and this study focused on identifying dosing errors rather than timing.
- The research evaluated 189 sepsis patients, finding that only 50.8% received the correct antibiotic dose while 30.7% were under-dosed and 25.9% overdosed, with vancomycin showing the highest under-dosing rate.
- Factors like age, shock, and pre-existing conditions were linked to higher mortality rates, but surprisingly, the dosing errors did not correlate with increased mortality risk.
Background: Ventilator-associated events are common in mechanically ventilated patients. They are associated with more days on mechanical ventilation, longer intensive care unit (ICU) stay, and increased risk of mortality. Theoretically, interventions that prevent ventilator-associated events should also reduce associated morbidity.
View Article and Find Full Text PDFOver the past decade, there have been major improvements to the care of mechanically ventilated patients (MVPs). Earlier initiatives used the concept of ventilator care bundles (sets of interventions), with a primary focus on reducing ventilator-associated pneumonia. However, recent evidence has led to a more comprehensive approach: The ABCDE bundle (Awakening and Breathing trial Coordination, Delirium management and Early mobilization).
View Article and Find Full Text PDFThe Middle East Respiratory syndrome coronavirus (MERS-CoV) has been responsible for multiple health care-associated outbreaks. We investigated whether high-touch surfaces in 3 rooms of laboratory-confirmed MERS-CoV patients were contaminated with MERS-CoV RNA. We found 2 out of 51 surfaces were contaminated with MERS-CoV viral genetic material.
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