Publications by authors named "Raymenants K"
Dumping syndrome: Update on pathophysiology, diagnosis, and management.
Neurogastroenterol Motil
February 2025
Background: Dumping syndrome is a complex of gastrointestinal symptoms originally studied in peptic ulcer surgery patients. At present, it is most prevalent in patients who underwent bariatric, upper gastrointestinal cancer or anti-reflux surgery. The symptom pattern comprises early and late dumping symptoms.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to understand the natural history and prognostic factors of porto-sinusoidal vascular disorder (PSVD) by analyzing a large cohort of 587 patients across 27 centers, finding that the majority were asymptomatic at diagnosis, but many experienced complications related to portal hypertension.
- - Over a median follow-up of 68 months, 8.5% of patients underwent liver transplantation, while 19% died, highlighting significant risks like portal hypertension-related bleeding and ascites, as well as the impact of age and liver function on prognosis.
- - The findings indicate that the severity of underlying conditions and liver/renal function significantly influence survival chances, leading to the development of a nomogram for more accurate prognosis prediction in
Background/aims: Retrograde cricopharyngeus dysfunction (R-CPD) is a new clinical entity characterized by inability to belch and associated symptoms of loud gurgling noises, chest and/or abdominal pressure, abdominal bloating, and excessive flatulence. R-CPD can be treated with botulinum toxin (BT) injection in the upper esophageal sphincter. We hereby report patient demographics, symptomatology, and treatment results of a series of consecutive patients who presented at our center.
View Article and Find Full Text PDFBackground: Gastrointestinal dysmotility is frequently suspected in patients with gastroparesis, functional dyspepsia, and ileus, and in the intensive care unit. Monitoring of gastric motility in clinical practice remains challenging. A novel technology was developed to meet the medical need for a widely available bedside tool to monitor gastric motility continuously.
View Article and Find Full Text PDFBackground: Disorders of gut-brain interaction (DGBIs) have a complex pathophysiology that is often characterized by a relationship between food ingestion and triggering of symptoms. Understanding of the underlying mechanisms and the role of nutrients as a therapeutic target are rapidly evolving.
Aims And Methods: We performed a narrative review of the literature using the following keywords, their acronyms, and their associations: nutrients, disorders of gut-brain interaction; functional dyspepsia; malabsorption; irritable bowel syndrome; diarrhea; constipation.
Background: Functional dyspepsia (FD) is one of the most frequent conditions in gastroenterological outpatient health care. Most recent research in FD has shifted its focus to duodenal pathophysiological mechanisms, although current treatments still focus mainly the stomach.
Aim: The aim of the study was to provide a comprehensive overview of the pathophysiology of FD focusing on a paradigm shift from gastric towards duodenal mechanisms.
Understanding and managing patients with overlapping disorders of gut-brain interaction.
Lancet Gastroenterol Hepatol
April 2023
Disorders of gut-brain interaction (DGBI) are frequently encountered in clinical practice, and recommendations for diagnosis and management are well established. In a large subset of patients, more than one DGBI diagnosis is present. This group of patients with more than one DGBI diagnosis have higher symptom severity and impact than patients with only one DGBI diagnosis, and the management approach is not well established for those with overlapping diagnoses.
View Article and Find Full Text PDFArticle Synopsis
- Porto-sinusoidal vascular liver disorder (PSVD) is a rare condition that can lead to liver transplantation (LT), even when liver function is usually preserved, but there is limited data on LT outcomes for PSVD patients.!* -
- A study of 79 patients showed that common reasons for LT were refractory ascites and hepatic encephalopathy, with a post-LT survival rate of approximately 82% at one year and decreasing over five years; factors like severe associated conditions and high bilirubin or creatinine levels were linked to poorer survival outcomes.!* -
- While LT for PSVD can yield good results, ongoing severe conditions at the time of transplantation and certain lab values are critical for assessing patient prognosis,
Editorial: refractory reflux sensitivity-A place for baclofen? Authors' reply.
Aliment Pharmacol Ther
August 2022
Background: Proton pump inhibitors (PPI) have no effect on non-acid reflux events which can continue to provoke gastro-oesophageal reflux disease (GERD) symptoms. Baclofen, a γ-aminobutyric acid agonist, can decrease non-acid reflux but its symptomatic benefit in refractory GERD symptoms is understudied.
Aims: To assess the efficacy of baclofen 10 mg t.