Publications by authors named "Raymart Macasaet"
Ehrlichiosis is a tickborne illness that can lead to an increased risk of death without appropriate treatment. According to Centers for Disease Control and Prevention, there has been a rise in incidence. We present a case of an immunocompetent patient who reported tick removal after hiking.
View Article and Find Full Text PDFTrichilemmal carcinoma (TC) is a rare, low-grade, malignant adnexal tumor. It is usually less than 3 cm long and arises from the external root sheath of the hair follicle, most commonly in sun-exposed areas of the body. The treatment of choice is wide local excision with tumor-free margins.
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- The study examines the hypothesis that viral persistence of SARS-CoV-2 RNA may explain post-COVID symptoms by analyzing various bodily samples from patients experiencing these symptoms.
- A systematic review of literature yielded six relevant studies out of 322 identified, involving 678 COVID-19 survivors, with mixed methodological quality across the studies.
- Preliminary findings suggest SARS-CoV-2 RNA might persist in patients with post-COVID symptoms shortly after infection; however, biases and lack of a control group restrict the ability to draw definitive conclusions about this persistence.
The use of adeno-associated virus (AAV) vectors in gene therapy has demonstrated great potential in treating genetic disorders. However, infusion-associated reactions (IARs) pose a significant challenge to the safety and efficacy of AAV-based gene therapy. This review provides a comprehensive summary of the current understanding of IARs to AAV therapy, including their underlying mechanisms, clinical presentation, and treatment options.
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- The review explores whether antiviral medications given during the acute phase of COVID-19 can help reduce the risk of developing long-COVID symptoms.
- A comprehensive search of various medical databases identified 7 relevant studies, with high methodological quality in most.
- The findings are mixed, with some antivirals like Remdesivir showing potential benefits, while other drugs like Dexamethasone and Metformin also showed promise, though more research is necessary to make definitive conclusions.
Objective: This meta-analysis investigated the prevalence of post-COVID symptoms two-years after SARS-CoV-2 infection.
Methods: Electronic literature searches on PubMed, MEDLINE, CINAHL, EMBASE, Web of Science databases, and on medRxiv/bioRxiv preprint servers were conducted up to October 1, 2023. Studies reporting data on post-COVID symptoms at two-years after infection were included.