Association of immunity-related gene SNPs with Alzheimer's disease.

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder characterized by progressive cognitive decline. Genetic factors have been implicated in disease susceptibility as its etiology remains multifactorial. The and the genes, involved in immune responses, have emerged as potential candidates influencing AD risk.

APOE genotypes in Lebanon: distribution and association with hypercholesterolemia and Alzheimer's disease.

Aim: We first investigated the distribution of APOE genotypes in Lebanese general population and Alzheimer's disease study (ADS) groups, and compared it with 1000 genomes populations. Then, we assessed eventual association between APOE genotypes, hypercholesterolemia and Alzheimer's disease (AD).

Materials & Methods: This cross-sectional study was conducted on 591 individuals.