Publications by authors named "Rayaan Mahfouz"
Are Circulating Immune Cells a Determinant of Pancreatic Cancer Risk? A Prospective Study Using Epigenetic Cell Count Measures.
Cancer Epidemiol Biomarkers Prev
December 2021
Article Synopsis
- Immune cells may contribute to pancreatic cancer development, yet studies haven’t thoroughly explored this connection prospectively.
- A nested case-control study within the EPIC project analyzed immune cell counts in 502 individuals with pancreatic cancer compared to matched controls.
- While individual immune cell counts did not show a significant relationship with cancer risk, higher levels of regulatory T cells and lower levels of CD8 cells were linked to increased risk shortly after diagnosis, suggesting potential late-stage tumor development.